Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4794
MIM: 604548
HGNC: 7799
Ensembl: ENSG00000146232
Variants:
dbSNP: 4794
ClinVar: 4794
TCGA: ENSG00000146232
COSMIC: NFKBIE
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38486128 | 2024 | NFKBIE mutations are selected by the tumor microenvironment and contribute to immune escape in chronic lymphocytic leukemia. | 1 |
| 38486128 | 2024 | NFKBIE mutations are selected by the tumor microenvironment and contribute to immune escape in chronic lymphocytic leukemia. | 1 |
| 26587663 | 2016 | Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line. | 3 |
| 26870821 | 2016 | Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children. | 10 |
| 27670424 | 2016 | Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. | 33 |
| 26587663 | 2016 | Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line. | 3 |
| 26870821 | 2016 | Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children. | 10 |
| 27670424 | 2016 | Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. | 33 |
| 25987724 | 2015 | Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia. | 49 |
| 26226212 | 2015 | Galectin-1 reduced the effect of LPS on the IL-6 production in decidual cells by inhibiting LPS on the stimulation of IκBζ. | 13 |
| 26343386 | 2015 | Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. | 106 |
| 25987724 | 2015 | Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia. | 49 |
| 26226212 | 2015 | Galectin-1 reduced the effect of LPS on the IL-6 production in decidual cells by inhibiting LPS on the stimulation of IκBζ. | 13 |
| 26343386 | 2015 | Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. | 106 |
| 23615073 | 2013 | Vitamin C forestalls cigarette smoke induced NF-κB activation in alveolar epithelial cells. | 5 |
Citation
Dessen P
NFKBIE (NFKB inhibitor epsilon)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41532/nfkbie
