NFKBIL1 (NFKB inhibitor like 1)

2008-12-01  

Identity

HGNC
NFKBIL1
LOCATION
6p21.33
LOCUSID
4795
ALIAS
IKBL,NFKBIL

Other Information

Locus ID:

NCBI: 4795
MIM: 601022
HGNC: 7800
Ensembl: ENSG00000204498

Variants:

dbSNP: 4795
ClinVar: 4795
TCGA: ENSG00000204498
COSMIC: NFKBIL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204498ENST00000376145A0A0A0MRT5
ENSG00000204498ENST00000376146Q5STV6
ENSG00000204498ENST00000376148Q9UBC1
ENSG00000204498ENST00000496233F2Z390

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
125097892003Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.20
166348652006Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis.19
171199502007Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis.17
191438142009Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.17
209331062011Autoimmune hepatitis, HLA and extended haplotypes.17
150186492004Complex genetic predisposition in adult and juvenile rheumatoid arthritis.15
111130702000Susceptibility to severe ulcerative colitis is associated with polymorphism in the central MHC gene IKBL.11

Citation

Dessen P

NFKBIL1 (NFKB inhibitor like 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50494/nfkbil1