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NFKBIZ (NFKB inhibitor zeta)

Identity

Alias_namesnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Alias_symbol (synonym)MAIL
FLJ34463
INAP
Other aliasIKBZ
HGNC (Hugo) NFKBIZ
LocusID (NCBI) 64332
Atlas_Id 53613
Location 3q12.3  [Link to chromosome band 3q12]
Location_base_pair Starts at 101849514 and ends at 101861025 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADARB1 (21q22.3) / NFKBIZ (3q12.3)NFKBIZ (3q12.3) / NFKBIZ (3q12.3)NFKBIZ (3q12.3) / RGS19 (20q13.33)
RAB1B (11q13.2) / NFKBIZ (3q12.3)SFTPB (2p11.2) / NFKBIZ (3q12.3)SNX17 (2p23.3) / NFKBIZ (3q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NFKBIZ   29805
Cards
Entrez_Gene (NCBI)NFKBIZ  64332  NFKB inhibitor zeta
AliasesIKBZ; INAP; MAIL
GeneCards (Weizmann)NFKBIZ
Ensembl hg19 (Hinxton)ENSG00000144802 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144802 [Gene_View]  ENSG00000144802 [Sequence]  chr3:101849514-101861025 [Contig_View]  NFKBIZ [Vega]
ICGC DataPortalENSG00000144802
TCGA cBioPortalNFKBIZ
AceView (NCBI)NFKBIZ
Genatlas (Paris)NFKBIZ
WikiGenes64332
SOURCE (Princeton)NFKBIZ
Genetics Home Reference (NIH)NFKBIZ
Genomic and cartography
GoldenPath hg38 (UCSC)NFKBIZ  -     chr3:101849514-101861025 +  3q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFKBIZ  -     3q12.3   [Description]    (hg19-Feb_2009)
GoldenPathNFKBIZ - 3q12.3 [CytoView hg19]  NFKBIZ - 3q12.3 [CytoView hg38]
ImmunoBaseENSG00000144802
Mapping of homologs : NCBINFKBIZ [Mapview hg19]  NFKBIZ [Mapview hg38]
OMIM608004   
Gene and transcription
Genbank (Entrez)AB037925 AB074898 AF548362 AK054787 AK091782
RefSeq transcript (Entrez)NM_001005474 NM_031419
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NFKBIZ
Cluster EST : UnigeneHs.319171 [ NCBI ]
CGAP (NCI)Hs.319171
Alternative Splicing GalleryENSG00000144802
Gene ExpressionNFKBIZ [ NCBI-GEO ]   NFKBIZ [ EBI - ARRAY_EXPRESS ]   NFKBIZ [ SEEK ]   NFKBIZ [ MEM ]
Gene Expression Viewer (FireBrowse)NFKBIZ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64332
GTEX Portal (Tissue expression)NFKBIZ
Human Protein AtlasENSG00000144802-NFKBIZ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYH8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYH8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYH8
Splice isoforms : SwissVarQ9BYH8
PhosPhoSitePlusQ9BYH8
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)NFKBIZ
DMDM Disease mutations64332
Blocks (Seattle)NFKBIZ
SuperfamilyQ9BYH8
Human Protein Atlas [tissue]ENSG00000144802-NFKBIZ [tissue]
Peptide AtlasQ9BYH8
HPRD09217
IPIIPI00027741   IPI00470452   IPI00300903   IPI00946877   IPI00790954   IPI00946535   IPI00797051   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYH8
IntAct (EBI)Q9BYH8
FunCoupENSG00000144802
BioGRIDNFKBIZ
STRING (EMBL)NFKBIZ
ZODIACNFKBIZ
Ontologies - Pathways
QuickGOQ9BYH8
Ontology : AmiGOprotein binding  nucleus  inflammatory response  nuclear speck  cytoplasmic ribonucleoprotein granule  positive regulation of inflammatory response  T cell receptor signaling pathway  positive regulation of T-helper 17 cell differentiation  
Ontology : EGO-EBIprotein binding  nucleus  inflammatory response  nuclear speck  cytoplasmic ribonucleoprotein granule  positive regulation of inflammatory response  T cell receptor signaling pathway  positive regulation of T-helper 17 cell differentiation  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkNFKBIZ
Atlas of Cancer Signalling NetworkNFKBIZ
Wikipedia pathwaysNFKBIZ
Orthology - Evolution
OrthoDB64332
GeneTree (enSembl)ENSG00000144802
Phylogenetic Trees/Animal Genes : TreeFamNFKBIZ
HOGENOMQ9BYH8
Homologs : HomoloGeneNFKBIZ
Homology/Alignments : Family Browser (UCSC)NFKBIZ
Gene fusions - Rearrangements
Fusion : QuiverNFKBIZ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFKBIZ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFKBIZ
dbVarNFKBIZ
ClinVarNFKBIZ
1000_GenomesNFKBIZ 
Exome Variant ServerNFKBIZ
ExAC (Exome Aggregation Consortium)ENSG00000144802
GNOMAD BrowserENSG00000144802
Varsome BrowserNFKBIZ
Genetic variants : HAPMAP64332
Genomic Variants (DGV)NFKBIZ [DGVbeta]
DECIPHERNFKBIZ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFKBIZ 
Mutations
ICGC Data PortalNFKBIZ 
TCGA Data PortalNFKBIZ 
Broad Tumor PortalNFKBIZ
OASIS PortalNFKBIZ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFKBIZ  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNFKBIZ
Mutations and Diseases : HGMDNFKBIZ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFKBIZ
DgiDB (Drug Gene Interaction Database)NFKBIZ
DoCM (Curated mutations)NFKBIZ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFKBIZ (select a term)
intoGenNFKBIZ
Cancer3DNFKBIZ(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608004   
Orphanet
DisGeNETNFKBIZ
MedgenNFKBIZ
Genetic Testing Registry NFKBIZ
NextProtQ9BYH8 [Medical]
TSGene64332
GENETestsNFKBIZ
Target ValidationNFKBIZ
Huge Navigator NFKBIZ [HugePedia]
snp3D : Map Gene to Disease64332
BioCentury BCIQNFKBIZ
ClinGenNFKBIZ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64332
Chemical/Pharm GKB GenePA134990505
Clinical trialNFKBIZ
Miscellaneous
canSAR (ICR)NFKBIZ (select the gene name)
DataMed IndexNFKBIZ
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFKBIZ
EVEXNFKBIZ
GoPubMedNFKBIZ
iHOPNFKBIZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Nov 13 17:57:56 CET 2019
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