Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NIFK (nucleolar protein interacting with the FHA domain of MKI67)

Identity

Alias_namesMKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
Alias_symbol (synonym)Nopp34
hNIFK
Other alias
HGNC (Hugo) NIFK
LocusID (NCBI) 84365
Atlas_Id 56695
Location 2q14.3  [Link to chromosome band 2q14]
Location_base_pair Starts at 121726945 and ends at 121736927 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACSL3 (2q36.1) / NIFK (2q14.3)NIFK (2q14.3) / BTBD2 (19p13.3)NIFK (2q14.3) / SHOX (Xp22.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(2;19)(q14;p13) NIFK/BTBD2

External links

Nomenclature
HGNC (Hugo)NIFK   17838
Cards
Entrez_Gene (NCBI)NIFK  84365  nucleolar protein interacting with the FHA domain of MKI67
AliasesMKI67IP; Nopp34
GeneCards (Weizmann)NIFK
Ensembl hg19 (Hinxton)ENSG00000155438 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155438 [Gene_View]  ENSG00000155438 [Sequence]  chr2:121726945-121736927 [Contig_View]  NIFK [Vega]
ICGC DataPortalENSG00000155438
TCGA cBioPortalNIFK
AceView (NCBI)NIFK
Genatlas (Paris)NIFK
WikiGenes84365
SOURCE (Princeton)NIFK
Genetics Home Reference (NIH)NIFK
Genomic and cartography
GoldenPath hg38 (UCSC)NIFK  -     chr2:121726945-121736927 -  2q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NIFK  -     2q14.3   [Description]    (hg19-Feb_2009)
GoldenPathNIFK - 2q14.3 [CytoView hg19]  NIFK - 2q14.3 [CytoView hg38]
ImmunoBaseENSG00000155438
Mapping of homologs : NCBINIFK [Mapview hg19]  NIFK [Mapview hg38]
OMIM611970   
Gene and transcription
Genbank (Entrez)AB044971 AK291903 AK299814 AK311033 BC012457
RefSeq transcript (Entrez)NM_032390
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NIFK
Cluster EST : UnigeneHs.367842 [ NCBI ]
CGAP (NCI)Hs.367842
Alternative Splicing GalleryENSG00000155438
Gene ExpressionNIFK [ NCBI-GEO ]   NIFK [ EBI - ARRAY_EXPRESS ]   NIFK [ SEEK ]   NIFK [ MEM ]
Gene Expression Viewer (FireBrowse)NIFK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84365
GTEX Portal (Tissue expression)NIFK
Human Protein AtlasENSG00000155438-NIFK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYG3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYG3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYG3
Splice isoforms : SwissVarQ9BYG3
PhosPhoSitePlusQ9BYG3
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)hNIFK_FHA_Ki67_binding    Nucleotide-bd_a/b_plait_sf    RBD_domain_sf    RRM_dom   
Domain families : Pfam (Sanger)hNIFK_binding (PF12196)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam12196    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)NIFK
DMDM Disease mutations84365
Blocks (Seattle)NIFK
PDB (RSDB)2AFF   
PDB Europe2AFF   
PDB (PDBSum)2AFF   
PDB (IMB)2AFF   
Structural Biology KnowledgeBase2AFF   
SCOP (Structural Classification of Proteins)2AFF   
CATH (Classification of proteins structures)2AFF   
SuperfamilyQ9BYG3
Human Protein Atlas [tissue]ENSG00000155438-NIFK [tissue]
Peptide AtlasQ9BYG3
IPIIPI00154590   IPI01009013   IPI00916663   IPI00916807   IPI00915819   IPI00908705   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYG3
IntAct (EBI)Q9BYG3
FunCoupENSG00000155438
BioGRIDNIFK
STRING (EMBL)NIFK
ZODIACNIFK
Ontologies - Pathways
QuickGOQ9BYG3
Ontology : AmiGOcondensed nuclear chromosome  RNA binding  RNA binding  protein binding  nucleoplasm  nucleolus  cytoplasm  rRNA transcription  rRNA metabolic process  protein-containing complex assembly  
Ontology : EGO-EBIcondensed nuclear chromosome  RNA binding  RNA binding  protein binding  nucleoplasm  nucleolus  cytoplasm  rRNA transcription  rRNA metabolic process  protein-containing complex assembly  
NDEx NetworkNIFK
Atlas of Cancer Signalling NetworkNIFK
Wikipedia pathwaysNIFK
Orthology - Evolution
OrthoDB84365
GeneTree (enSembl)ENSG00000155438
Phylogenetic Trees/Animal Genes : TreeFamNIFK
HOGENOMQ9BYG3
Homologs : HomoloGeneNIFK
Homology/Alignments : Family Browser (UCSC)NIFK
Gene fusions - Rearrangements
Fusion : QuiverNIFK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNIFK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NIFK
dbVarNIFK
ClinVarNIFK
1000_GenomesNIFK 
Exome Variant ServerNIFK
ExAC (Exome Aggregation Consortium)ENSG00000155438
GNOMAD BrowserENSG00000155438
Varsome BrowserNIFK
Genetic variants : HAPMAP84365
Genomic Variants (DGV)NIFK [DGVbeta]
DECIPHERNIFK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNIFK 
Mutations
ICGC Data PortalNIFK 
TCGA Data PortalNIFK 
Broad Tumor PortalNIFK
OASIS PortalNIFK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNIFK  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNIFK
Mutations and Diseases : HGMDNIFK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NIFK
DgiDB (Drug Gene Interaction Database)NIFK
DoCM (Curated mutations)NIFK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NIFK (select a term)
intoGenNIFK
Cancer3DNIFK(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611970   
Orphanet
DisGeNETNIFK
MedgenNIFK
Genetic Testing Registry NIFK
NextProtQ9BYG3 [Medical]
TSGene84365
GENETestsNIFK
Target ValidationNIFK
Huge Navigator NIFK [HugePedia]
snp3D : Map Gene to Disease84365
BioCentury BCIQNIFK
ClinGenNIFK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84365
Chemical/Pharm GKB GenePA38470
Clinical trialNIFK
Miscellaneous
canSAR (ICR)NIFK (select the gene name)
DataMed IndexNIFK
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNIFK
EVEXNIFK
GoPubMedNIFK
iHOPNIFK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:58:02 CET 2019
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