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NME3 (NME/NM23 nucleoside diphosphate kinase 3)

Identity

Alias_namesnon-metastatic cells 3, protein expressed in
Alias_symbol (synonym)DR-nm23
NM23-H3
NDPKC
Other aliasNDPK-C
NM23H3
c371H6.2
HGNC (Hugo) NME3
LocusID (NCBI) 4832
Atlas_Id 41545
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1770320 and ends at 1771709 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTDSPL2 (15q15.3) / NME3 (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NME3   7851
Cards
Entrez_Gene (NCBI)NME3  4832  NME/NM23 nucleoside diphosphate kinase 3
AliasesDR-nm23; NDPK-C; NDPKC; NM23-H3; 
NM23H3; c371H6.2
GeneCards (Weizmann)NME3
Ensembl hg19 (Hinxton)ENSG00000103024 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103024 [Gene_View]  ENSG00000103024 [Sequence]  chr16:1770320-1771709 [Contig_View]  NME3 [Vega]
ICGC DataPortalENSG00000103024
TCGA cBioPortalNME3
AceView (NCBI)NME3
Genatlas (Paris)NME3
WikiGenes4832
SOURCE (Princeton)NME3
Genetics Home Reference (NIH)NME3
Genomic and cartography
GoldenPath hg38 (UCSC)NME3  -     chr16:1770320-1771709 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NME3  -     16p13.3   [Description]    (hg19-Feb_2009)
GoldenPathNME3 - 16p13.3 [CytoView hg19]  NME3 - 16p13.3 [CytoView hg38]
ImmunoBaseENSG00000103024
Mapping of homologs : NCBINME3 [Mapview hg19]  NME3 [Mapview hg38]
OMIM601817   
Gene and transcription
Genbank (Entrez)AK308663 BC000250 BG911570 U29656
RefSeq transcript (Entrez)NM_002513
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NME3
Cluster EST : UnigeneHs.514065 [ NCBI ]
CGAP (NCI)Hs.514065
Alternative Splicing GalleryENSG00000103024
Gene ExpressionNME3 [ NCBI-GEO ]   NME3 [ EBI - ARRAY_EXPRESS ]   NME3 [ SEEK ]   NME3 [ MEM ]
Gene Expression Viewer (FireBrowse)NME3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4832
GTEX Portal (Tissue expression)NME3
Human Protein AtlasENSG00000103024-NME3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13232   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13232  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13232
Splice isoforms : SwissVarQ13232
Catalytic activity : Enzyme2.7.4.6 [ Enzyme-Expasy ]   2.7.4.62.7.4.6 [ IntEnz-EBI ]   2.7.4.6 [ BRENDA ]   2.7.4.6 [ KEGG ]   
PhosPhoSitePlusQ13232
Domaine pattern : Prosite (Expaxy)NDP_KINASES (PS00469)   
Domains : Interpro (EBI)NDK-like_dom    NDK-like_dom_sf    Nucleoside_diP_kinase    Nucleoside_diP_kinase_AS   
Domain families : Pfam (Sanger)NDK (PF00334)   
Domain families : Pfam (NCBI)pfam00334   
Domain families : Smart (EMBL)NDK (SM00562)  
Conserved Domain (NCBI)NME3
DMDM Disease mutations4832
Blocks (Seattle)NME3
PDB (RSDB)1ZS6   
PDB Europe1ZS6   
PDB (PDBSum)1ZS6   
PDB (IMB)1ZS6   
Structural Biology KnowledgeBase1ZS6   
SCOP (Structural Classification of Proteins)1ZS6   
CATH (Classification of proteins structures)1ZS6   
SuperfamilyQ13232
Human Protein Atlas [tissue]ENSG00000103024-NME3 [tissue]
Peptide AtlasQ13232
HPRD03488
IPIIPI00012315   
Protein Interaction databases
DIP (DOE-UCLA)Q13232
IntAct (EBI)Q13232
FunCoupENSG00000103024
BioGRIDNME3
STRING (EMBL)NME3
ZODIACNME3
Ontologies - Pathways
QuickGOQ13232
Ontology : AmiGOnucleoside diphosphate kinase activity  protein binding  ATP binding  cytosol  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  apoptotic process  nucleobase-containing small molecule interconversion  metal ion binding  
Ontology : EGO-EBInucleoside diphosphate kinase activity  protein binding  ATP binding  cytosol  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  apoptotic process  nucleobase-containing small molecule interconversion  metal ion binding  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkNME3
Atlas of Cancer Signalling NetworkNME3
Wikipedia pathwaysNME3
Orthology - Evolution
OrthoDB4832
GeneTree (enSembl)ENSG00000103024
Phylogenetic Trees/Animal Genes : TreeFamNME3
HOGENOMQ13232
Homologs : HomoloGeneNME3
Homology/Alignments : Family Browser (UCSC)NME3
Gene fusions - Rearrangements
Fusion : QuiverNME3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNME3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NME3
dbVarNME3
ClinVarNME3
1000_GenomesNME3 
Exome Variant ServerNME3
ExAC (Exome Aggregation Consortium)ENSG00000103024
GNOMAD BrowserENSG00000103024
Varsome BrowserNME3
Genetic variants : HAPMAP4832
Genomic Variants (DGV)NME3 [DGVbeta]
DECIPHERNME3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNME3 
Mutations
ICGC Data PortalNME3 
TCGA Data PortalNME3 
Broad Tumor PortalNME3
OASIS PortalNME3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNME3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNME3
Mutations and Diseases : HGMDNME3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NME3
DgiDB (Drug Gene Interaction Database)NME3
DoCM (Curated mutations)NME3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NME3 (select a term)
intoGenNME3
Cancer3DNME3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601817   
Orphanet
DisGeNETNME3
MedgenNME3
Genetic Testing Registry NME3
NextProtQ13232 [Medical]
TSGene4832
GENETestsNME3
Target ValidationNME3
Huge Navigator NME3 [HugePedia]
snp3D : Map Gene to Disease4832
BioCentury BCIQNME3
ClinGenNME3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4832
Chemical/Pharm GKB GenePA31656
Clinical trialNME3
Miscellaneous
canSAR (ICR)NME3 (select the gene name)
DataMed IndexNME3
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNME3
EVEXNME3
GoPubMedNME3
iHOPNME3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:58:13 CET 2019
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