NME6 (NME/NM23 nucleoside diphosphate kinase 6)

2003-11-01  

Identity

HGNC
NME6
LOCATION
3p21.31
LOCUSID
10201
ALIAS
IPIA-ALPHA,NDK

Other Information

Locus ID:

NCBI: 10201
MIM: 608294
HGNC: 20567
Ensembl: ENSG00000172113

Variants:

dbSNP: 10201
ClinVar: 10201
TCGA: ENSG00000172113
COSMIC: NME6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172113ENST00000415053O75414
ENSG00000172113ENST00000415644O75414
ENSG00000172113ENST00000418431F2Z2J2
ENSG00000172113ENST00000421967A0A0C4DG91
ENSG00000172113ENST00000425930C9J9V6
ENSG00000172113ENST00000426689O75414
ENSG00000172113ENST00000435684O75414
ENSG00000172113ENST00000442597O75414
ENSG00000172113ENST00000444069A0A2R8Y547
ENSG00000172113ENST00000447314C9JQB1
ENSG00000172113ENST00000447724C9J867
ENSG00000172113ENST00000451657O75414
ENSG00000172113ENST00000452211O75414
ENSG00000172113ENST00000454531F2Z2J2
ENSG00000172113ENST00000456495C9J1J2
ENSG00000172113ENST00000642710A0A2R8Y547
ENSG00000172113ENST00000643011A0A2R8Y7V2
ENSG00000172113ENST00000643457O75414

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
Metabolic pathwaysKEGGhsa01100
Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTPKEGGhsa_M00052
Adenine ribonucleotide biosynthesis, IMP => ADP,ATPKEGGM00049
Guanine ribonucleotide biosynthesis IMP => GDP,GTPKEGGM00050
Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTPKEGGM00052
Adenine ribonucleotide biosynthesis, IMP => ADP,ATPKEGGhsa_M00049
Guanine ribonucleotide biosynthesis IMP => GDP,GTPKEGGhsa_M00050

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
271209982016Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population.0

Citation

Dessen P

NME6 (NME/NM23 nucleoside diphosphate kinase 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41547/nme6