NMT2 (N-myristoyltransferase 2)

2007-02-01 Affiliation

Identity

HGNC

NMT2

LOCATION

10p13

LOCUSID

9397

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9397
MIM: 603801
HGNC: 7858
Ensembl: ENSG00000152465

Variants:

dbSNP: 9397
ClinVar: 9397
TCGA: ENSG00000152465
COSMIC: NMT2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000152465	ENST00000378150	Q5VUC6
ENSG00000152465	ENST00000378165	O60551

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Disease	REACTOME	R-HSA-1643685
Infectious disease	REACTOME	R-HSA-5663205
HIV Infection	REACTOME	R-HSA-162906
HIV Life Cycle	REACTOME	R-HSA-162587
Late Phase of HIV Life Cycle	REACTOME	R-HSA-162599
Assembly Of The HIV Virion	REACTOME	R-HSA-175474
Synthesis And Processing Of GAG, GAGPOL Polyproteins	REACTOME	R-HSA-174495
Membrane binding and targetting of GAG proteins	REACTOME	R-HSA-174490
Signal Transduction	REACTOME	R-HSA-162582
Visual phototransduction	REACTOME	R-HSA-2187338
The phototransduction cascade	REACTOME	R-HSA-2514856
Inactivation, recovery and regulation of the phototransduction cascade	REACTOME	R-HSA-2514859

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
16123142	2005	Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.	39
18089753	2008	N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef.	11
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
11731439	2001	Novel target genes of the Ah (dioxin) receptor: transcriptional induction of N-myristoyltransferase 2.	10
16530191	2006	N-myristoyltransferase 2 expression in human colon cancer: cross-talk between the calpain and caspase system.	8
26621918	2016	Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA.	8
16364039	2006	Genes associated with telomerase activity levels in esophageal carcinoma cell lines.	3
17568424	2007	Is the disruption of an N-myristoyltransferase (NMT2) associated with hypoplastic testes?	1

Citation

Dessen P

NMT2 (N-myristoyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45992/nmt2