Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NOCT (nocturnin)

Identity

Alias_namesCCRN4L
CCR4-like (carbon catabolite repression 4, S.cerevisiae)
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
Alias_symbol (synonym)CCR4L
Ccr4c
NOC
Other alias
HGNC (Hugo) NOCT
LocusID (NCBI) 25819
Atlas_Id 46547
Location 4q31.1  [Link to chromosome band 4q31]
Location_base_pair Starts at 139015781 and ends at 139045939 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NOCT (4q31.1) / CRLF3 (17q11.2)NOCT (4q31.1) / MMS19 (10q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NOCT   14254
Cards
Entrez_Gene (NCBI)NOCT  25819  nocturnin
AliasesCCR4L; CCRN4L; Ccr4c; NOC
GeneCards (Weizmann)NOCT
Ensembl hg19 (Hinxton)ENSG00000151014 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151014 [Gene_View]  ENSG00000151014 [Sequence]  chr4:139015781-139045939 [Contig_View]  NOCT [Vega]
ICGC DataPortalENSG00000151014
TCGA cBioPortalNOCT
AceView (NCBI)NOCT
Genatlas (Paris)NOCT
WikiGenes25819
SOURCE (Princeton)NOCT
Genetics Home Reference (NIH)NOCT
Genomic and cartography
GoldenPath hg38 (UCSC)NOCT  -     chr4:139015781-139045939 +  4q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NOCT  -     4q31.1   [Description]    (hg19-Feb_2009)
GoldenPathNOCT - 4q31.1 [CytoView hg19]  NOCT - 4q31.1 [CytoView hg38]
Genome Data Viewer NCBINOCT [Mapview hg19]  
OMIM608468   
Gene and transcription
Genbank (Entrez)AF183961 AF199493 AF199494 BC021963 BC023512
RefSeq transcript (Entrez)NM_012118
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NOCT
Alternative Splicing GalleryENSG00000151014
Gene ExpressionNOCT [ NCBI-GEO ]   NOCT [ EBI - ARRAY_EXPRESS ]   NOCT [ SEEK ]   NOCT [ MEM ]
Gene Expression Viewer (FireBrowse)NOCT [ Firebrowse - Broad ]
GenevisibleExpression of NOCT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25819
GTEX Portal (Tissue expression)NOCT
Human Protein AtlasENSG00000151014-NOCT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UK39   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UK39  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UK39
Splice isoforms : SwissVarQ9UK39
PhosPhoSitePlusQ9UK39
Domains : Interpro (EBI)Deadenylase_nocturnin    Endo/exonu/phosph_ase_sf    Endo/exonuclease/phosphatase    Nocturnin   
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Conserved Domain (NCBI)NOCT
DMDM Disease mutations25819
PDB (RSDB)6BT1    6BT2    6MAL    6NF0   
PDB Europe6BT1    6BT2    6MAL    6NF0   
PDB (PDBSum)6BT1    6BT2    6MAL    6NF0   
PDB (IMB)6BT1    6BT2    6MAL    6NF0   
Structural Biology KnowledgeBase6BT1    6BT2    6MAL    6NF0   
SCOP (Structural Classification of Proteins)6BT1    6BT2    6MAL    6NF0   
CATH (Classification of proteins structures)6BT1    6BT2    6MAL    6NF0   
SuperfamilyQ9UK39
Human Protein Atlas [tissue]ENSG00000151014-NOCT [tissue]
Peptide AtlasQ9UK39
HPRD16337
IPIIPI00015890   IPI00744490   
Protein Interaction databases
DIP (DOE-UCLA)Q9UK39
IntAct (EBI)Q9UK39
FunCoupENSG00000151014
BioGRIDNOCT
STRING (EMBL)NOCT
ZODIACNOCT
Ontologies - Pathways
QuickGOQ9UK39
Ontology : AmiGO3'-5'-exoribonuclease activity  deadenylation-dependent decapping of nuclear-transcribed mRNA  P-body  mRNA binding  poly(A)-specific ribonuclease activity  nucleus  nucleoplasm  cytoplasm  mitochondrion  transcription by RNA polymerase II  NADP metabolic process  circadian rhythm  response to extracellular stimulus  negative regulation of gene expression  dephosphorylation  NADP phosphatase activity  response to lipopolysaccharide  circadian regulation of gene expression  cytoplasmic mRNA processing body assembly  regulation of circadian rhythm  positive regulation of fat cell differentiation  negative regulation of osteoblast differentiation  regulation of embryonic development  metal ion binding  mRNA stabilization  perinuclear region of cytoplasm  RNA phosphodiester bond hydrolysis, exonucleolytic  NADPH phosphatase activity  
Ontology : EGO-EBI3'-5'-exoribonuclease activity  deadenylation-dependent decapping of nuclear-transcribed mRNA  P-body  mRNA binding  poly(A)-specific ribonuclease activity  nucleus  nucleoplasm  cytoplasm  mitochondrion  transcription by RNA polymerase II  NADP metabolic process  circadian rhythm  response to extracellular stimulus  negative regulation of gene expression  dephosphorylation  NADP phosphatase activity  response to lipopolysaccharide  circadian regulation of gene expression  cytoplasmic mRNA processing body assembly  regulation of circadian rhythm  positive regulation of fat cell differentiation  negative regulation of osteoblast differentiation  regulation of embryonic development  metal ion binding  mRNA stabilization  perinuclear region of cytoplasm  RNA phosphodiester bond hydrolysis, exonucleolytic  NADPH phosphatase activity  
NDEx NetworkNOCT
Atlas of Cancer Signalling NetworkNOCT
Wikipedia pathwaysNOCT
Orthology - Evolution
OrthoDB25819
GeneTree (enSembl)ENSG00000151014
Phylogenetic Trees/Animal Genes : TreeFamNOCT
HOGENOMQ9UK39
Homologs : HomoloGeneNOCT
Homology/Alignments : Family Browser (UCSC)NOCT
Gene fusions - Rearrangements
Fusion : QuiverNOCT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNOCT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOCT
dbVarNOCT
ClinVarNOCT
1000_GenomesNOCT 
Exome Variant ServerNOCT
GNOMAD BrowserENSG00000151014
Varsome BrowserNOCT
Genetic variants : HAPMAP25819
Genomic Variants (DGV)NOCT [DGVbeta]
DECIPHERNOCT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNOCT 
Mutations
ICGC Data PortalNOCT 
TCGA Data PortalNOCT 
Broad Tumor PortalNOCT
OASIS PortalNOCT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOCT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNOCT
Mutations and Diseases : HGMDNOCT
BioMutaselect NOCT
DgiDB (Drug Gene Interaction Database)NOCT
DoCM (Curated mutations)NOCT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOCT (select a term)
intoGenNOCT
Cancer3DNOCT (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608468   
Orphanet
DisGeNETNOCT
MedgenNOCT
Genetic Testing Registry NOCT
NextProtQ9UK39 [Medical]
TSGene25819
GENETestsNOCT
Open Targets GeneticsENSG00000151014  [validation]
snp3D : Map Gene to Disease25819
BioCentury BCIQNOCT
ClinGenNOCT
Clinical trials, drugs, therapy
Protein Interactions : CTD25819
Pharm GKB GenePA26176
Clinical trialNOCT
Miscellaneous
canSAR (ICR)NOCT (select the gene name)
HarmonizomeNOCT
DataMed IndexNOCT
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOCT
EVEXNOCT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 11 20:02:39 CEST 2020

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