Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NOLC1 (nucleolar and coiled-body phosphoprotein 1)

Identity

Alias_symbol (synonym)P130
KIAA0035
NOPP140
NOPP130
Other aliasNS5ATP13
HGNC (Hugo) NOLC1
LocusID (NCBI) 9221
Atlas_Id 51051
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102152176 and ends at 102163871 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAP1 (7p22.3) / NOLC1 (10q24.32)MMS19 (10q24.1) / NOLC1 (10q24.32)NISCH (3p21.1) / NOLC1 (10q24.32)
NOLC1 (10q24.32) / ARL15 (5q11.2)NOLC1 (10q24.32) / BIVM-ERCC5 (13q33.1)NOLC1 (10q24.32) / CIDEB (14q12)
NOLC1 (10q24.32) / IYD (6q25.1)NOLC1 (10q24.32) / SHROOM3 (4q21.1)NOLC1 (10q24.32) / ZDHHC22 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  PPRC1/NOLC1 (10q24)

External links

Nomenclature
HGNC (Hugo)NOLC1   15608
Cards
Entrez_Gene (NCBI)NOLC1  9221  nucleolar and coiled-body phosphoprotein 1
AliasesNOPP130; NOPP140; NS5ATP13; P130
GeneCards (Weizmann)NOLC1
Ensembl hg19 (Hinxton)ENSG00000166197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166197 [Gene_View]  ENSG00000166197 [Sequence]  chr10:102152176-102163871 [Contig_View]  NOLC1 [Vega]
ICGC DataPortalENSG00000166197
TCGA cBioPortalNOLC1
AceView (NCBI)NOLC1
Genatlas (Paris)NOLC1
WikiGenes9221
SOURCE (Princeton)NOLC1
Genetics Home Reference (NIH)NOLC1
Genomic and cartography
GoldenPath hg38 (UCSC)NOLC1  -     chr10:102152176-102163871 +  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NOLC1  -     10q24.32   [Description]    (hg19-Feb_2009)
GoldenPathNOLC1 - 10q24.32 [CytoView hg19]  NOLC1 - 10q24.32 [CytoView hg38]
ImmunoBaseENSG00000166197
Mapping of homologs : NCBINOLC1 [Mapview hg19]  NOLC1 [Mapview hg38]
OMIM602394   
Gene and transcription
Genbank (Entrez)AI937215 AK056755 AK225101 AK314363 AL520884
RefSeq transcript (Entrez)NM_001284388 NM_001284389 NM_004741
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NOLC1
Cluster EST : UnigeneHs.523238 [ NCBI ]
CGAP (NCI)Hs.523238
Alternative Splicing GalleryENSG00000166197
Gene ExpressionNOLC1 [ NCBI-GEO ]   NOLC1 [ EBI - ARRAY_EXPRESS ]   NOLC1 [ SEEK ]   NOLC1 [ MEM ]
Gene Expression Viewer (FireBrowse)NOLC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9221
GTEX Portal (Tissue expression)NOLC1
Human Protein AtlasENSG00000166197-NOLC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14978   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14978  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14978
Splice isoforms : SwissVarQ14978
PhosPhoSitePlusQ14978
Domaine pattern : Prosite (Expaxy)LISH (PS50896)   
Domains : Interpro (EBI)LisH    SRP40_C   
Domain families : Pfam (Sanger)SRP40_C (PF05022)   
Domain families : Pfam (NCBI)pfam05022   
Conserved Domain (NCBI)NOLC1
DMDM Disease mutations9221
Blocks (Seattle)NOLC1
SuperfamilyQ14978
Human Protein Atlas [tissue]ENSG00000166197-NOLC1 [tissue]
Peptide AtlasQ14978
IPIIPI00292387   IPI00216654   IPI00908873   
Protein Interaction databases
DIP (DOE-UCLA)Q14978
IntAct (EBI)Q14978
FunCoupENSG00000166197
BioGRIDNOLC1
STRING (EMBL)NOLC1
ZODIACNOLC1
Ontologies - Pathways
QuickGOQ14978
Ontology : AmiGOmitotic cell cycle  RNA polymerase I core binding  fibrillar center  DNA binding  DNA-binding transcription factor activity  RNA binding  protein binding  ATP binding  GTP binding  nucleoplasm  nucleolus  nucleolus  cytoplasm  rRNA processing  regulation of translation  response to osmotic stress  nucleolus organization  transcription factor binding  nuclear localization sequence binding  positive regulation of cell proliferation  neural crest formation  neural crest cell development  Cajal body  protein domain specific binding  box C/D snoRNP complex  box H/ACA snoRNP complex  box H/ACA snoRNA metabolic process  box C/D snoRNA binding  box H/ACA snoRNA binding  regulation of protein import into nucleus  positive regulation of transcription, DNA-templated  protein heterodimerization activity  box C/D snoRNP complex binding  box H/ACA snoRNP complex binding  
Ontology : EGO-EBImitotic cell cycle  RNA polymerase I core binding  fibrillar center  DNA binding  DNA-binding transcription factor activity  RNA binding  protein binding  ATP binding  GTP binding  nucleoplasm  nucleolus  nucleolus  cytoplasm  rRNA processing  regulation of translation  response to osmotic stress  nucleolus organization  transcription factor binding  nuclear localization sequence binding  positive regulation of cell proliferation  neural crest formation  neural crest cell development  Cajal body  protein domain specific binding  box C/D snoRNP complex  box H/ACA snoRNP complex  box H/ACA snoRNA metabolic process  box C/D snoRNA binding  box H/ACA snoRNA binding  regulation of protein import into nucleus  positive regulation of transcription, DNA-templated  protein heterodimerization activity  box C/D snoRNP complex binding  box H/ACA snoRNP complex binding  
NDEx NetworkNOLC1
Atlas of Cancer Signalling NetworkNOLC1
Wikipedia pathwaysNOLC1
Orthology - Evolution
OrthoDB9221
GeneTree (enSembl)ENSG00000166197
Phylogenetic Trees/Animal Genes : TreeFamNOLC1
HOGENOMQ14978
Homologs : HomoloGeneNOLC1
Homology/Alignments : Family Browser (UCSC)NOLC1
Gene fusions - Rearrangements
Fusion : QuiverNOLC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNOLC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOLC1
dbVarNOLC1
ClinVarNOLC1
1000_GenomesNOLC1 
Exome Variant ServerNOLC1
ExAC (Exome Aggregation Consortium)ENSG00000166197
GNOMAD BrowserENSG00000166197
Varsome BrowserNOLC1
Genetic variants : HAPMAP9221
Genomic Variants (DGV)NOLC1 [DGVbeta]
DECIPHERNOLC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNOLC1 
Mutations
ICGC Data PortalNOLC1 
TCGA Data PortalNOLC1 
Broad Tumor PortalNOLC1
OASIS PortalNOLC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOLC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNOLC1
Mutations and Diseases : HGMDNOLC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NOLC1
DgiDB (Drug Gene Interaction Database)NOLC1
DoCM (Curated mutations)NOLC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOLC1 (select a term)
intoGenNOLC1
Cancer3DNOLC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602394   
Orphanet
DisGeNETNOLC1
MedgenNOLC1
Genetic Testing Registry NOLC1
NextProtQ14978 [Medical]
TSGene9221
GENETestsNOLC1
Target ValidationNOLC1
Huge Navigator NOLC1 [HugePedia]
snp3D : Map Gene to Disease9221
BioCentury BCIQNOLC1
ClinGenNOLC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9221
Chemical/Pharm GKB GenePA31679
Clinical trialNOLC1
Miscellaneous
canSAR (ICR)NOLC1 (select the gene name)
DataMed IndexNOLC1
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOLC1
EVEXNOLC1
GoPubMedNOLC1
iHOPNOLC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:58:19 CET 2019
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