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NOTCH2NLB (notch 2 N-terminal like B)

Identity

Other aliasN2N
NOTCH2NL
NOTCH2NLA
HGNC (Hugo) NOTCH2NLB
LocusID (NCBI) 100996763
Atlas_Id 80625
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 148599807 and ends at 148679764 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)NOTCH2NLB   53923
Cards
Entrez_Gene (NCBI)NOTCH2NLB  100996763  notch 2 N-terminal like B
AliasesN2N; NOTCH2NL; NOTCH2NLA
GeneCards (Weizmann)NOTCH2NLB
Ensembl hg19 (Hinxton)ENSG00000286019 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000286019 [Gene_View]  ENSG00000286019 [Sequence]  chr1:148599807-148679764 [Contig_View]  NOTCH2NLB [Vega]
ICGC DataPortalENSG00000286019
TCGA cBioPortalNOTCH2NLB
AceView (NCBI)NOTCH2NLB
Genatlas (Paris)NOTCH2NLB
WikiGenes100996763
SOURCE (Princeton)NOTCH2NLB
Genetics Home Reference (NIH)NOTCH2NLB
Genomic and cartography
GoldenPath hg38 (UCSC)NOTCH2NLB  -     chr1:148599807-148679764 -  1q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NOTCH2NLB  -     1q21.2   [Description]    (hg19-Feb_2009)
GoldenPathNOTCH2NLB - 1q21.2 [CytoView hg19]  NOTCH2NLB - 1q21.2 [CytoView hg38]
ImmunoBaseENSG00000286019
genome Data Viewer NCBINOTCH2NLB [Mapview hg19]  
OMIM618024   
Gene and transcription
Genbank (Entrez)MH721899
RefSeq transcript (Entrez)NM_001364007 NM_001364008
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NOTCH2NLB
Alternative Splicing GalleryENSG00000286019
Gene ExpressionNOTCH2NLB [ NCBI-GEO ]   NOTCH2NLB [ EBI - ARRAY_EXPRESS ]   NOTCH2NLB [ SEEK ]   NOTCH2NLB [ MEM ]
Gene Expression Viewer (FireBrowse)NOTCH2NLB [ Firebrowse - Broad ]
GenevisibleExpression of NOTCH2NLB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100996763
GTEX Portal (Tissue expression)NOTCH2NLB
Human Protein AtlasENSG00000286019-NOTCH2NLB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0DPK3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0DPK3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0DPK3
Splice isoforms : SwissVarP0DPK3
PhosPhoSitePlusP0DPK3
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)   
Domains : Interpro (EBI)EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS   
Domain families : Pfam (Sanger)EGF (PF00008)    EGF_CA (PF07645)   
Domain families : Pfam (NCBI)pfam00008    pfam07645   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
Conserved Domain (NCBI)NOTCH2NLB
DMDM Disease mutations100996763
Blocks (Seattle)NOTCH2NLB
SuperfamilyP0DPK3
Human Protein Atlas [tissue]ENSG00000286019-NOTCH2NLB [tissue]
Peptide AtlasP0DPK3
Protein Interaction databases
DIP (DOE-UCLA)P0DPK3
IntAct (EBI)P0DPK3
FunCoupENSG00000286019
BioGRIDNOTCH2NLB
STRING (EMBL)NOTCH2NLB
ZODIACNOTCH2NLB
Ontologies - Pathways
QuickGOP0DPK3
Ontology : AmiGONotch binding  calcium ion binding  protein binding  extracellular region  Notch signaling pathway  cerebral cortex development  positive regulation of Notch signaling pathway  
Ontology : EGO-EBINotch binding  calcium ion binding  protein binding  extracellular region  Notch signaling pathway  cerebral cortex development  positive regulation of Notch signaling pathway  
NDEx NetworkNOTCH2NLB
Atlas of Cancer Signalling NetworkNOTCH2NLB
Wikipedia pathwaysNOTCH2NLB
Orthology - Evolution
OrthoDB100996763
GeneTree (enSembl)ENSG00000286019
Phylogenetic Trees/Animal Genes : TreeFamNOTCH2NLB
HOGENOMP0DPK3
Homologs : HomoloGeneNOTCH2NLB
Homology/Alignments : Family Browser (UCSC)NOTCH2NLB
Gene fusions - Rearrangements
Fusion : QuiverNOTCH2NLB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNOTCH2NLB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOTCH2NLB
dbVarNOTCH2NLB
ClinVarNOTCH2NLB
1000_GenomesNOTCH2NLB 
Exome Variant ServerNOTCH2NLB
GNOMAD BrowserENSG00000286019
Varsome BrowserNOTCH2NLB
Genetic variants : HAPMAP100996763
Genomic Variants (DGV)NOTCH2NLB [DGVbeta]
DECIPHERNOTCH2NLB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNOTCH2NLB 
Mutations
ICGC Data PortalNOTCH2NLB 
TCGA Data PortalNOTCH2NLB 
Broad Tumor PortalNOTCH2NLB
OASIS PortalNOTCH2NLB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNOTCH2NLB
BioMutasearch NOTCH2NLB
DgiDB (Drug Gene Interaction Database)NOTCH2NLB
DoCM (Curated mutations)NOTCH2NLB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOTCH2NLB (select a term)
intoGenNOTCH2NLB
Cancer3DNOTCH2NLB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618024   
Orphanet
DisGeNETNOTCH2NLB
MedgenNOTCH2NLB
Genetic Testing Registry NOTCH2NLB
NextProtP0DPK3 [Medical]
TSGene100996763
GENETestsNOTCH2NLB
Target ValidationNOTCH2NLB
Huge Navigator NOTCH2NLB [HugePedia]
snp3D : Map Gene to Disease100996763
BioCentury BCIQNOTCH2NLB
ClinGenNOTCH2NLB
Clinical trials, drugs, therapy
Protein Interactions : CTD100996763
Clinical trialNOTCH2NLB
Miscellaneous
canSAR (ICR)NOTCH2NLB (select the gene name)
HarmonizomeNOTCH2NLB
DataMed IndexNOTCH2NLB
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOTCH2NLB
EVEXNOTCH2NLB
GoPubMedNOTCH2NLB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jul 10 20:28:04 CEST 2020

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