NOVA1 (NOVA alternative splicing regulator 1)

2003-06-01  

Identity

HGNC
LOCATION
14q12
LOCUSID
ALIAS
Nova-1
FUSION GENES

Other Information

Locus ID:

NCBI: 4857
MIM: 602157
HGNC: 7886
Ensembl: ENSG00000139910

Variants:

dbSNP: 4857
ClinVar: 4857
TCGA: ENSG00000139910
COSMIC: NOVA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139910ENST00000344429P51513
ENSG00000139910ENST00000347476G8JLA5
ENSG00000139910ENST00000449198J3KQU3
ENSG00000139910ENST00000465357P51513
ENSG00000139910ENST00000483536F8VYI3
ENSG00000139910ENST00000539517P51513
ENSG00000139910ENST00000546546H0YHZ1
ENSG00000139910ENST00000547619F8W659
ENSG00000139910ENST00000549146F8VW64
ENSG00000139910ENST00000549571F8VWX1
ENSG00000139910ENST00000574031I3L2B5

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195843462009Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.93
182186282008Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV.35
252990732014MiR-181b-5p downregulates NOVA1 to suppress proliferation, migration and invasion and promote apoptosis in astrocytoma.25
263916412015MicroRNA-339, an epigenetic modulating target is involved in human gastric carcinogenesis through targeting NOVA1.16
273184972017Implications of NOVA1 suppression within the microenvironment of gastric cancer: association with immune cell dysregulation.16
196806352009Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients.15
266736172016NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal.15
243122782013TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.12
246081712014High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.12
261086722015Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.12

Citation

Dessen P

NOVA1 (NOVA alternative splicing regulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41560/nova1