NOVA2 (NOVA alternative splicing regulator 2)

2003-02-01  

Identity

HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
ANOVA,NEDASB,NOVA-2,NOVA3
FUSION GENES

Other Information

Locus ID:

NCBI: 4858
MIM: 601991
HGNC: 7887
Ensembl: ENSG00000104967

Variants:

dbSNP: 4858
ClinVar: 4858
TCGA: ENSG00000104967
COSMIC: NOVA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104967ENST00000263257Q9UNW9
ENSG00000104967ENST00000596784M0R1A0

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
174362422007Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A.33
308295702019A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing.6
318320682019MiR-7-5p suppresses tumor metastasis of non-small cell lung cancer by targeting NOVA2.5
310144802019The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage.4
321970732020De Novo Frameshift Variants in the Neuronal Splicing Factor NOVA2 Result in a Common C-Terminal Extension and Cause a Severe Form of Neurodevelopmental Disorder.1

Citation

Dessen P

NOVA2 (NOVA alternative splicing regulator 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41561/nova2