| Nomenclature |
|---|
| HGNC (Hugo) | NPAS1 7894 |
| Cards |
|---|
| Entrez_Gene (NCBI) | NPAS1 4861 neuronal PAS domain protein 1 |
| Aliases | MOP5; PASD5; bHLHe11 |
| GeneCards (Weizmann) | NPAS1 |
| Ensembl hg19 (Hinxton) | ENSG00000130751 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000130751 [Gene_View] ENSG00000130751 [Sequence] chr19:47035329-47045775 [Contig_View] NPAS1 [Vega] |
| ICGC DataPortal | ENSG00000130751 |
| TCGA cBioPortal | NPAS1 |
| AceView (NCBI) | NPAS1 |
| Genatlas (Paris) | NPAS1 |
| WikiGenes | 4861 |
| SOURCE (Princeton) | NPAS1 |
| Genetics Home Reference (NIH) | NPAS1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | NPAS1 - chr19:47035329-47045775 + 19q13.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | NPAS1 - 19q13.32 [Description] (hg19-Feb_2009) |
| GoldenPath | NPAS1 - 19q13.32 [CytoView hg19] NPAS1 - 19q13.32 [CytoView hg38] |
| ImmunoBase | ENSG00000130751 |
| Mapping of homologs : NCBI | NPAS1 [Mapview hg19] NPAS1 [Mapview hg38] |
| OMIM | 603346 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB054002 AK299128 BC039016 CA420408 U51628 |
| RefSeq transcript (Entrez) | NM_001321086 NM_002517 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | NPAS1 |
| Cluster EST : Unigene | Hs.79564 [ NCBI ] |
| CGAP (NCI) | Hs.79564 |
| Alternative Splicing Gallery | ENSG00000130751 |
| Gene Expression | NPAS1 [ NCBI-GEO ] NPAS1 [ EBI - ARRAY_EXPRESS ]
NPAS1 [ SEEK ] NPAS1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | NPAS1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 4861 |
| GTEX Portal (Tissue expression) | NPAS1 |
| Human Protein Atlas | ENSG00000130751-NPAS1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q99742 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q99742 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q99742 |
| Splice isoforms : SwissVar | Q99742 |
| PhosPhoSitePlus | Q99742 |
| Domaine pattern : Prosite (Expaxy) | BHLH (PS50888) PAS (PS50112) |
| Domains : Interpro (EBI) | bHLH_dom HLH_DNA-bd_sf PAS PAS-like_dom_sf PAS_fold PAS_fold_3 |
| Domain families : Pfam (Sanger) | HLH (PF00010) PAS (PF00989) PAS_3 (PF08447) |
| Domain families : Pfam (NCBI) | pfam00010 pfam00989 pfam08447 |
| Domain families : Smart (EMBL) | HLH (SM00353) PAS (SM00091) |
| Conserved Domain (NCBI) | NPAS1 |
| DMDM Disease mutations | 4861 |
| Blocks (Seattle) | NPAS1 |
| Superfamily | Q99742 |
| Human Protein Atlas [tissue] | ENSG00000130751-NPAS1 [tissue] |
| Peptide Atlas | Q99742 |
| HPRD | 09136 |
| IPI | IPI00293815 IPI00910071 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q99742 |
| IntAct (EBI) | Q99742 |
| FunCoup | ENSG00000130751 |
| BioGRID | NPAS1 |
| STRING (EMBL) | NPAS1 |
| ZODIAC | NPAS1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q99742 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific startle response DNA binding DNA-binding transcription factor activity nucleus regulation of transcription by RNA polymerase II central nervous system development maternal behavior negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II protein heterodimerization activity |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific startle response DNA binding DNA-binding transcription factor activity nucleus regulation of transcription by RNA polymerase II central nervous system development maternal behavior negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II protein heterodimerization activity |
| NDEx Network | NPAS1 |
| Atlas of Cancer Signalling Network | NPAS1 |
| Wikipedia pathways | NPAS1 |
| Orthology - Evolution |
|---|
| OrthoDB | 4861 |
| GeneTree (enSembl) | ENSG00000130751 |
| Phylogenetic Trees/Animal Genes : TreeFam | NPAS1 |
| HOGENOM | Q99742 |
| Homologs : HomoloGene | NPAS1 |
| Homology/Alignments : Family Browser (UCSC) | NPAS1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | NPAS1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | NPAS1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | NPAS1 |
| dbVar | NPAS1 |
| ClinVar | NPAS1 |
| 1000_Genomes | NPAS1 |
| Exome Variant Server | NPAS1 |
| ExAC (Exome Aggregation Consortium) | ENSG00000130751 |
| GNOMAD Browser | ENSG00000130751 |
| Varsome Browser | NPAS1 |
| Genetic variants : HAPMAP | 4861 |
| Genomic Variants (DGV) | NPAS1 [DGVbeta] |
| DECIPHER | NPAS1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | NPAS1 |
| Mutations |
|---|
| ICGC Data Portal | NPAS1 |
| TCGA Data Portal | NPAS1 |
| Broad Tumor Portal | NPAS1 |
| OASIS Portal | NPAS1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | NPAS1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | NPAS1 |
| Mutations and Diseases : HGMD | NPAS1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search NPAS1 |
| DgiDB (Drug Gene Interaction Database) | NPAS1 |
| DoCM (Curated mutations) | NPAS1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | NPAS1 (select a term) |
| intoGen | NPAS1 |
| Cancer3D | NPAS1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 603346 |
| Orphanet | |
| DisGeNET | NPAS1 |
| Medgen | NPAS1 |
| Genetic Testing Registry | NPAS1
|
| NextProt | Q99742 [Medical] |
| TSGene | 4861 |
| GENETests | NPAS1 |
| Target Validation | NPAS1 |
| Huge Navigator |
NPAS1 [HugePedia] |
| snp3D : Map Gene to Disease | 4861 |
| BioCentury BCIQ | NPAS1 |
| ClinGen | NPAS1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 4861 |
| Chemical/Pharm GKB Gene | PA31695 |
| Clinical trial | NPAS1 |
| Miscellaneous |
|---|
| canSAR (ICR) | NPAS1 (select the gene name) |
| DataMed Index | NPAS1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 10 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | NPAS1 |
| EVEX | NPAS1 |
| GoPubMed | NPAS1 |
| iHOP | NPAS1 |
