NPPC (natriuretic peptide C)

2009-03-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
CNP,CNP2

Other Information

Locus ID:

NCBI: 4880
MIM: 600296
HGNC: 7941
Ensembl: ENSG00000163273

Variants:

dbSNP: 4880
ClinVar: 4880
TCGA: ENSG00000163273
COSMIC: NPPC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163273ENST00000295440P23582
ENSG00000163273ENST00000409852P23582

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Physiological factorsREACTOMER-HSA-5578768
Fluid shear stress and atherosclerosisKEGGko05418
Fluid shear stress and atherosclerosisKEGGhsa05418

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374934512023C-type natriuretic peptide induces inotropic and lusitropic effects in human 3D-engineered cardiac tissue: Implications for the regulation of cardiac function in humans.1
374934512023C-type natriuretic peptide induces inotropic and lusitropic effects in human 3D-engineered cardiac tissue: Implications for the regulation of cardiac function in humans.1
351206712022A novel variant of NPPC causes abnormal post-translational cleavage: A candidate gene for premature ovarian insufficiency.0
351206712022A novel variant of NPPC causes abnormal post-translational cleavage: A candidate gene for premature ovarian insufficiency.0
317947872020C-type natriuretic peptide plasma levels and whole blood mRNA expression show different trends in adolescents with different degree of endothelial dysfunction.7
318939502020Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide).6
322680702020C-type natriuretic peptide (CNP)/guanylate cyclase B (GC-B) system and endothelin-1(ET-1)/ET receptor A and B system in human vasculature.1
317947872020C-type natriuretic peptide plasma levels and whole blood mRNA expression show different trends in adolescents with different degree of endothelial dysfunction.7
318939502020Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide).6
322680702020C-type natriuretic peptide (CNP)/guanylate cyclase B (GC-B) system and endothelin-1(ET-1)/ET receptor A and B system in human vasculature.1
310720472019C-type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature.51
310753022019C-type natriuretic peptide signaling in human follicular environment and its relation with oocyte maturation.3
314314482019Urinary Amino-Terminal Pro-C-Type Natriuretic Peptide: A Novel Marker of Chronic Kidney Disease in Diabetes.7
310720472019C-type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature.51
310753022019C-type natriuretic peptide signaling in human follicular environment and its relation with oocyte maturation.3

Citation

Dessen P

NPPC (natriuretic peptide C)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50830/nppc