NPTX1 (neuronal pentraxin 1)

2015-05-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
NP1
FUSION GENES

Other Information

Locus ID:

NCBI: 4884
MIM: 602367
HGNC: 7952
Ensembl: ENSG00000171246

Variants:

dbSNP: 4884
ClinVar: 4884
TCGA: ENSG00000171246
COSMIC: NPTX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171246ENST00000306773Q15818

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
171512772006Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain.25
245297092014NPTX1 regulates neural lineage specification from human pluripotent stem cells.16
260388302015Altered Markers of Cortical γ-Aminobutyric Acid Neuronal Activity in Schizophrenia: Role of the NARP Gene.15
250532812015Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.7
250294232014Long-acting progestin-only contraceptives enhance human endometrial stromal cell expressed neuronal pentraxin-1 and reactive oxygen species to promote endothelial cell apoptosis.6
256466942015NPTX1 is a novel epigenetic regulation gene and associated with prognosis in lung cancer.6
295015302018Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease.5
293453912018NPTX1 inhibits colon cancer cell proliferation through down-regulating cyclin A2 and CDK2 expression.3
254985042015Neuronal pentraxin 1 expression is regulated by hypoxia inducible factor-1α.1
161156962005Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin.0

Citation

Dessen P

NPTX1 (neuronal pentraxin 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55213/nptx1