NPW (neuropeptide W)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
L8,L8C,PPL8,PPNPW

Other Information

Locus ID:

NCBI: 283869
MIM: 607997
HGNC: 30509
Ensembl: ENSG00000183971

Variants:

dbSNP: 283869
ClinVar: 283869
TCGA: ENSG00000183971
COSMIC: NPW

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183971ENST00000566435H3BT17
ENSG00000183971ENST00000567649H3BT42

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
127195372003Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8.37
121306462002Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.0
129599972003A role for neuropeptide W in the regulation of feeding behavior.0
228267472011Analgesic neuropeptide W suppresses seizures in the brain revealed by rational repositioning and peptide engineering.0
252702692014Gastric neuropeptide W is regulated by meal-related nutrients.0
265360902015Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7.0

Citation

Dessen P

NPW (neuropeptide W)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70956/npw