Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NPY2R (neuropeptide Y receptor Y2)

Identity

Other aliasNPY2-R
HGNC (Hugo) NPY2R
LocusID (NCBI) 4887
Atlas_Id 43703
Location 4q32.1  [Link to chromosome band 4q32]
Location_base_pair Starts at 155208629 and ends at 155217078 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NPY2R   7957
Cards
Entrez_Gene (NCBI)NPY2R  4887  neuropeptide Y receptor Y2
AliasesNPY2-R
GeneCards (Weizmann)NPY2R
Ensembl hg19 (Hinxton)ENSG00000185149 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185149 [Gene_View]  ENSG00000185149 [Sequence]  chr4:155208629-155217078 [Contig_View]  NPY2R [Vega]
ICGC DataPortalENSG00000185149
TCGA cBioPortalNPY2R
AceView (NCBI)NPY2R
Genatlas (Paris)NPY2R
WikiGenes4887
SOURCE (Princeton)NPY2R
Genetics Home Reference (NIH)NPY2R
Genomic and cartography
GoldenPath hg38 (UCSC)NPY2R  -     chr4:155208629-155217078 +  4q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NPY2R  -     4q32.1   [Description]    (hg19-Feb_2009)
GoldenPathNPY2R - 4q32.1 [CytoView hg19]  NPY2R - 4q32.1 [CytoView hg38]
ImmunoBaseENSG00000185149
Mapping of homologs : NCBINPY2R [Mapview hg19]  NPY2R [Mapview hg38]
OMIM162642   
Gene and transcription
Genbank (Entrez)BC075052 BC075053 U32500 U36269 U42389
RefSeq transcript (Entrez)NM_000910 NM_001370180
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NPY2R
Cluster EST : UnigeneHs.37125 [ NCBI ]
CGAP (NCI)Hs.37125
Alternative Splicing GalleryENSG00000185149
Gene ExpressionNPY2R [ NCBI-GEO ]   NPY2R [ EBI - ARRAY_EXPRESS ]   NPY2R [ SEEK ]   NPY2R [ MEM ]
Gene Expression Viewer (FireBrowse)NPY2R [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4887
GTEX Portal (Tissue expression)NPY2R
Human Protein AtlasENSG00000185149-NPY2R [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49146   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49146  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49146
Splice isoforms : SwissVarP49146
PhosPhoSitePlusP49146
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NPY2_rcpt    NPY_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)NPY2R
DMDM Disease mutations4887
Blocks (Seattle)NPY2R
PDB (RSDB)2IK3   
PDB Europe2IK3   
PDB (PDBSum)2IK3   
PDB (IMB)2IK3   
Structural Biology KnowledgeBase2IK3   
SCOP (Structural Classification of Proteins)2IK3   
CATH (Classification of proteins structures)2IK3   
SuperfamilyP49146
Human Protein Atlas [tissue]ENSG00000185149-NPY2R [tissue]
Peptide AtlasP49146
HPRD01216
IPIIPI00026065   
Protein Interaction databases
DIP (DOE-UCLA)P49146
IntAct (EBI)P49146
FunCoupENSG00000185149
BioGRIDNPY2R
STRING (EMBL)NPY2R
ZODIACNPY2R
Ontologies - Pathways
QuickGOP49146
Ontology : AmiGOpeptide YY receptor activity  behavioral fear response  positive regulation of peptide secretion  outflow tract morphogenesis  cardiac left ventricle morphogenesis  neuropeptide Y receptor activity  calcium channel regulator activity  protein binding  plasma membrane  integral component of plasma membrane  cilium  G protein-coupled receptor signaling pathway  adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  nitric oxide mediated signal transduction  aging  locomotory behavior  positive regulation of cell-substrate adhesion  positive regulation of dopamine secretion  signaling receptor activity  negative regulation of cAMP-mediated signaling  positive regulation of smooth muscle contraction  positive regulation of circadian sleep/wake cycle, non-REM sleep  secretion  negative regulation of secretion  regulation of sensory perception of pain  negative regulation of synaptic transmission, glutamatergic  negative regulation of excitatory postsynaptic potential  non-motile cilium  negative regulation of feeding behavior  
Ontology : EGO-EBIpeptide YY receptor activity  behavioral fear response  positive regulation of peptide secretion  outflow tract morphogenesis  cardiac left ventricle morphogenesis  neuropeptide Y receptor activity  calcium channel regulator activity  protein binding  plasma membrane  integral component of plasma membrane  cilium  G protein-coupled receptor signaling pathway  adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  nitric oxide mediated signal transduction  aging  locomotory behavior  positive regulation of cell-substrate adhesion  positive regulation of dopamine secretion  signaling receptor activity  negative regulation of cAMP-mediated signaling  positive regulation of smooth muscle contraction  positive regulation of circadian sleep/wake cycle, non-REM sleep  secretion  negative regulation of secretion  regulation of sensory perception of pain  negative regulation of synaptic transmission, glutamatergic  negative regulation of excitatory postsynaptic potential  non-motile cilium  negative regulation of feeding behavior  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkNPY2R
Atlas of Cancer Signalling NetworkNPY2R
Wikipedia pathwaysNPY2R
Orthology - Evolution
OrthoDB4887
GeneTree (enSembl)ENSG00000185149
Phylogenetic Trees/Animal Genes : TreeFamNPY2R
HOGENOMP49146
Homologs : HomoloGeneNPY2R
Homology/Alignments : Family Browser (UCSC)NPY2R
Gene fusions - Rearrangements
Fusion : QuiverNPY2R
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNPY2R [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NPY2R
dbVarNPY2R
ClinVarNPY2R
1000_GenomesNPY2R 
Exome Variant ServerNPY2R
ExAC (Exome Aggregation Consortium)ENSG00000185149
GNOMAD BrowserENSG00000185149
Varsome BrowserNPY2R
Genetic variants : HAPMAP4887
Genomic Variants (DGV)NPY2R [DGVbeta]
DECIPHERNPY2R [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNPY2R 
Mutations
ICGC Data PortalNPY2R 
TCGA Data PortalNPY2R 
Broad Tumor PortalNPY2R
OASIS PortalNPY2R [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNPY2R  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNPY2R
Mutations and Diseases : HGMDNPY2R
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NPY2R
DgiDB (Drug Gene Interaction Database)NPY2R
DoCM (Curated mutations)NPY2R (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NPY2R (select a term)
intoGenNPY2R
Cancer3DNPY2R(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM162642   
Orphanet
DisGeNETNPY2R
MedgenNPY2R
Genetic Testing Registry NPY2R
NextProtP49146 [Medical]
TSGene4887
GENETestsNPY2R
Target ValidationNPY2R
Huge Navigator NPY2R [HugePedia]
snp3D : Map Gene to Disease4887
BioCentury BCIQNPY2R
ClinGenNPY2R
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4887
Chemical/Pharm GKB GenePA31741
Clinical trialNPY2R
Miscellaneous
canSAR (ICR)NPY2R (select the gene name)
DataMed IndexNPY2R
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNPY2R
EVEXNPY2R
GoPubMedNPY2R
iHOPNPY2R
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:58:31 CET 2019
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