NR2F6 (nuclear receptor subfamily 2 group F member 6)

2003-02-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
EAR-2,EAR2,ERBAL2
FUSION GENES

Other Information

Locus ID:

NCBI: 2063
MIM: 132880
HGNC: 7977
Ensembl: ENSG00000160113

Variants:

dbSNP: 2063
ClinVar: 2063
TCGA: ENSG00000160113
COSMIC: NR2F6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160113ENST00000291442P10588
ENSG00000160113ENST00000291442F1D8R3
ENSG00000160113ENST00000596878M0R175

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280

References

Pubmed IDYearTitleCitations
313241862019Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression.14
216968852011The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells.11
239751952013A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.8
239751952013A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.8
296700992018Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.8
277755882016NR2F6 Expression Correlates with Pelvic Lymph Node Metastasis and Poor Prognosis in Early-Stage Cervical Cancer.7
212474192011Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription.6
289225622017Association between polymorphisms in microRNA target sites and survival in early-stage non-small cell lung cancer.1
308956192019Nuclear orphan receptor NR2F6 confers cisplatin resistance in epithelial ovarian cancer cells by activating the Notch3 signaling pathway.0
311686892019MiR-142-3p suppresses the proliferation, migration and invasion through inhibition of NR2F6 in lung adenocarcinoma.0

Citation

Dessen P

NR2F6 (nuclear receptor subfamily 2 group F member 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41572/nr2f6