NREP (neuronal regeneration related protein)

2008-07-01  

Identity

HGNC
NREP
LOCATION
5q22.1
LOCUSID
9315
ALIAS
C5orf13,D4S114,P311,PRO1873,PTZ17,SEZ17
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9315
MIM: 607332
HGNC: 16834
Ensembl: ENSG00000134986

Variants:

dbSNP: 9315
ClinVar: 9315
TCGA: ENSG00000134986
COSMIC: NREP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134986ENST00000257435Q16612
ENSG00000134986ENST00000379671Q16612
ENSG00000134986ENST00000395634Q16612
ENSG00000134986ENST00000419114Q16612
ENSG00000134986ENST00000446294Q16612
ENSG00000134986ENST00000447165Q16612
ENSG00000134986ENST00000450761Q16612
ENSG00000134986ENST00000453526Q16612
ENSG00000134986ENST00000455559Q16612
ENSG00000134986ENST00000508161D6R9Y7
ENSG00000134986ENST00000508870Q16612
ENSG00000134986ENST00000509025D6REJ5
ENSG00000134986ENST00000509427Q16612
ENSG00000134986ENST00000509979D6R982
ENSG00000134986ENST00000513100D6RIC9
ENSG00000134986ENST00000514515D6REJ5
ENSG00000134986ENST00000515855D6R982

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
162298092005Regulation of glioma cell migration by serine-phosphorylated P311.33
124175742002P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype.30
204049112010Investigating the role of P311 in the hypertrophic scar.25
253366512014Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3).16
266164072015P311 promotes renal fibrosis via TGFβ1/Smad signaling.16
164846842006Identification of P311 as a potential gene regulating alveolar generation.15
279391322017Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-β1 to -β3 Translation.7
279060992016P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression.5
279271302017P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation.5
229679772012[Effects of P 311 on the migration of epidermal stem cells in mice with superficial partial-thickness burn and injured cell model in vitro].3

Citation

Dessen P

NREP (neuronal regeneration related protein)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50160/nrep