Identity
HGNC
LOCATION
10p11.22
LOCUSID
ALIAS
BDCA4,CD304,NP1,NRP,VEGF165R
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8829
MIM: 602069
HGNC: 8004
Ensembl: ENSG00000099250
Variants:
dbSNP: 8829
ClinVar: 8829
TCGA: ENSG00000099250
COSMIC: NRP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134850558 | Macular Degeneration | Disease | ClinicalAnnotation | associated | PD | 26426212 | |
| PA164746012 | ranibizumab | Chemical | ClinicalAnnotation | associated | PD | 26426212 | |
| PA30086 | KDR | Gene | Pathway | associated | 20124951 | ||
| PA37302 | VEGFA | Gene | Pathway | associated | 20124951 | ||
| PA37303 | VEGFB | Gene | Pathway | associated | 20124951 | ||
| PA37304 | VEGFC | Gene | Pathway | associated | 20124951 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37533240 | 2024 | Sema3A Alleviates the Malignant Behaviors of Gastric Cancer Cells by Inhibiting NRP-1. | 2 |
| 37878035 | 2024 | Expression of placental growth factor, neuropilin-1, and neuropilin-2 in primary pterygium tissue. | 0 |
| 37943081 | 2024 | CD304 + adipose tissue-derived mesenchymal stem cell abundance in autologous fat grafts highly correlates with improvement of localized pain syndromes. | 0 |
| 38220212 | 2024 | NRP1 Induces Enhanced Stemness and Chemoresistance in Glioma Cells via YAP. | 0 |
| 38324585 | 2024 | Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells. | 3 |
| 38674009 | 2024 | DNA G-Quadruplex in NRP1 Promoter Facilitates SARS-CoV-2 Infection. | 0 |
| 37533240 | 2024 | Sema3A Alleviates the Malignant Behaviors of Gastric Cancer Cells by Inhibiting NRP-1. | 2 |
| 37878035 | 2024 | Expression of placental growth factor, neuropilin-1, and neuropilin-2 in primary pterygium tissue. | 0 |
| 37943081 | 2024 | CD304 + adipose tissue-derived mesenchymal stem cell abundance in autologous fat grafts highly correlates with improvement of localized pain syndromes. | 0 |
| 38220212 | 2024 | NRP1 Induces Enhanced Stemness and Chemoresistance in Glioma Cells via YAP. | 0 |
| 38324585 | 2024 | Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells. | 3 |
| 38674009 | 2024 | DNA G-Quadruplex in NRP1 Promoter Facilitates SARS-CoV-2 Infection. | 0 |
| 36333630 | 2023 | NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer. | 8 |
| 36376373 | 2023 | Hepatocellular carcinoma cells loss lenvatinib efficacy in vitro through autophagy and hypoxia response-derived neuropilin-1 degradation. | 6 |
| 36811396 | 2023 | Targeting neuropilin-1 abolishes anti-PD-1-upregulated regulatory T cells and synergizes with 4-1BB agonist for liver cancer treatment. | 3 |
Citation
Dessen P
NRP1 (neuropilin 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41582/nrp1
