NSRP1 (nuclear speckle splicing regulatory protein 1)

2015-02-01  

Identity

HGNC
NSRP1
LOCATION
17q11.2
LOCUSID
84081
ALIAS
CCDC55,HSPC095,NSrp70
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84081
MIM: 616173
HGNC: 25305
Ensembl: ENSG00000126653

Variants:

dbSNP: 84081
ClinVar: 84081
TCGA: ENSG00000126653
COSMIC: NSRP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126653ENST00000247026Q9H0G5
ENSG00000126653ENST00000394826H7BYM1
ENSG00000126653ENST00000475652J3QS82
ENSG00000126653ENST00000479218J3QS82
ENSG00000126653ENST00000580103K7ERM9
ENSG00000126653ENST00000584154J3KT62
ENSG00000126653ENST00000584317J3QLV5
ENSG00000126653ENST00000584423J3QRI6
ENSG00000126653ENST00000585881K7EK40
ENSG00000126653ENST00000588614K7EMD8
ENSG00000126653ENST00000589608K7EQJ6
ENSG00000126653ENST00000612959A0A024QZ33

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
190471282008Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.99
264757442015The CCDC55 couples cannabinoid receptor CNR1 to a putative DISC1 schizophrenia pathway.3
267971312016Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity.2
251763462014Aberrant proteomic expression of NSRP70 and its clinical implications and connection to the transcriptional level in adult acute leukemia.1

Citation

Dessen P

NSRP1 (nuclear speckle splicing regulatory protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55003/nsrp1