NTM (neurotrimin)

2013-03-01  

Identity

HGNC
NTM
LOCATION
11q25
LOCUSID
50863
ALIAS
CEPU-1,HNT,IGLON2,NTRI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 50863
MIM: 607938
HGNC: 17941
Ensembl: ENSG00000182667

Variants:

dbSNP: 50863
ClinVar: 50863
TCGA: ENSG00000182667
COSMIC: NTM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182667ENST00000374784Q9P121
ENSG00000182667ENST00000374786Q9P121
ENSG00000182667ENST00000374791Q9P121
ENSG00000182667ENST00000416661C9J0V2
ENSG00000182667ENST00000425719Q9P121
ENSG00000182667ENST00000427481F8W8Y1
ENSG00000182667ENST00000436745C9JK95
ENSG00000182667ENST00000457381H7BZ62
ENSG00000182667ENST00000539799F6WFR7
ENSG00000182667ENST00000550167F8VTR5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
128197832003OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.58
226614862012Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.25
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
210361972011NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.10
210361972011NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.10
230542442012A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm.7
153792482004The cloning and preliminarily functional analysis of the human neurotrimin gene.5
26334118201511q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures.4

Citation

Dessen P

NTM (neurotrimin)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53234/ntm