NTS (neurotensin)

2007-02-01  

Identity

HGNC
LOCATION
12q21.31
LOCUSID
ALIAS
NMN-125,NN,NT,NT/N,NTS1

Other Information

Locus ID:

NCBI: 4922
MIM: 162650
HGNC: 8038
Ensembl: ENSG00000133636

Variants:

dbSNP: 4922
ClinVar: 4922
TCGA: ENSG00000133636
COSMIC: NTS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133636ENST00000256010P30990
ENSG00000133636ENST00000256010Q6FH20
ENSG00000133636ENST00000551529G3V1X6

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA449841haloperidolChemicalMultilinkAnnotationassociated27023437

References

Pubmed IDYearTitleCitations
384238082024Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides.0
385225062024Neurotensin contributes to cholestatic liver disease potentially modulating matrix metalloprotease-7.0
384238082024Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides.0
385225062024Neurotensin contributes to cholestatic liver disease potentially modulating matrix metalloprotease-7.0
366807752023Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS(1)).5
369020252023Neurotensin and Its Involvement in Reproductive Functions: An Exhaustive Review of the Literature.2
369168832023Expression of Neurotensin and Its Receptors Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls.0
370474322023Neurotensin Gene rs2234762 C>G Variant Associates with Reduced Circulating Pro-NT Levels and Predicts Lower Insulin Resistance in Overweight/Obese Children.1
366807752023Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS(1)).5
369020252023Neurotensin and Its Involvement in Reproductive Functions: An Exhaustive Review of the Literature.2
369168832023Expression of Neurotensin and Its Receptors Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls.0
370474322023Neurotensin Gene rs2234762 C>G Variant Associates with Reduced Circulating Pro-NT Levels and Predicts Lower Insulin Resistance in Overweight/Obese Children.1
356114142022Elevated neurotensin levels among obese adolescents may be related to emotion dysregulation and impulsivity: a cross-sectional, case-control study.0
356114142022Elevated neurotensin levels among obese adolescents may be related to emotion dysregulation and impulsivity: a cross-sectional, case-control study.0
334935192021Suppression of the NTS-CPS1 regulatory axis by AFF1 in lung adenocarcinoma cells.1

Citation

Dessen P

NTS (neurotensin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46378/nts