NUAK2 (NUAK family kinase 2)

2007-02-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
SNARK
FUSION GENES

Other Information

Locus ID:

NCBI: 81788
MIM: 608131
HGNC: 29558
Ensembl: ENSG00000163545

Variants:

dbSNP: 81788
ClinVar: 81788
TCGA: ENSG00000163545
COSMIC: NUAK2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163545ENST00000367157Q9H093

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
207137142010Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle.43
153457182004Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness.19
214602522011AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.19
112847152001Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK.16
212423122011An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers.16
180234182008Identification of a novel substrate for TNFalpha-induced kinase NUAK2.13
196529462009Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.13
227965922012Activation of AMP-activated protein kinase alleviates high-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics.13
238311172013The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.12
258326542015NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.9

Citation

Dessen P

NUAK2 (NUAK family kinase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45666/nuak2