NUB1 (negative regulator of ubiquitin like proteins 1)

2007-02-01  

Identity

HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
BS4,NUB1L,NYREN18
FUSION GENES

Other Information

Locus ID:

NCBI: 51667
MIM: 607981
HGNC: 17623
Ensembl: ENSG00000013374

Variants:

dbSNP: 51667
ClinVar: 51667
TCGA: ENSG00000013374
COSMIC: NUB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000013374ENST00000413040H3BM14
ENSG00000013374ENST00000460712H7C5N1
ENSG00000013374ENST00000468404F8WDB6
ENSG00000013374ENST00000470229Q9Y5A7
ENSG00000013374ENST00000470316F8WDL9
ENSG00000013374ENST00000480714H7C5E1
ENSG00000013374ENST00000483358C9JRT6
ENSG00000013374ENST00000568733H3BM74

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371884632023FAT10 and NUB1L cooperate to activate the 26S proteasome.1
371884632023FAT10 and NUB1L cooperate to activate the 26S proteasome.1
348474502022SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1.2
348474502022SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1.2
327034842020Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.5
327034842020Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.5
310061602019Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy.3
310061602019Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy.3
280995102017Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination.5
280995102017Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination.5
272147912016NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradation.4
272147912016NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradation.4
262607932015NEDD8 Ultimate Buster 1 Long (NUB1L) Protein Suppresses Atypical Neddylation and Promotes the Proteasomal Degradation of Misfolded Proteins.19
262607932015NEDD8 Ultimate Buster 1 Long (NUB1L) Protein Suppresses Atypical Neddylation and Promotes the Proteasomal Degradation of Misfolded Proteins.19
235250432013Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance.49

Citation

Dessen P

NUB1 (negative regulator of ubiquitin like proteins 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43669/nub1