NUDT4 (nudix hydrolase 4)

2014-11-01  

Identity

HGNC
NUDT4
LOCATION
12q22
LOCUSID
11163
ALIAS
DIPP-2B,DIPP2,DIPP2alpha,DIPP2beta,HDCMB47P,NUDT4B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11163
MIM: 609229
HGNC: 8051
Ensembl: ENSG00000173598

Variants:

dbSNP: 11163
ClinVar: 11163
TCGA: ENSG00000173598
COSMIC: NUDT4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173598ENST00000337179Q9NZJ9
ENSG00000173598ENST00000415493Q9NZJ9
ENSG00000173598ENST00000415493A0A024RBD0
ENSG00000173598ENST00000546925F8VRR0
ENSG00000173598ENST00000547014Q9NZJ9
ENSG00000173598ENST00000548662A0A0C4DGJ4
ENSG00000173598ENST00000549992A0A0C4DGJ4
ENSG00000173598ENST00000550056F8VRL4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Inositol phosphate metabolismREACTOMER-HSA-1483249
Synthesis of pyrophosphates in the cytosolREACTOMER-HSA-1855167

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
107775682000Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family.29

Citation

Dessen P

NUDT4 (nudix hydrolase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71028/nudt4