NUTF2 (nuclear transport factor 2)

2013-01-01  

Identity

HGNC
NUTF2
LOCATION
16q22.1
LOCUSID
10204
ALIAS
NTF-2,NTF2,PP15
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10204
MIM: 605813
HGNC: 13722
Ensembl: ENSG00000102898

Variants:

dbSNP: 10204
ClinVar: 10204
TCGA: ENSG00000102898
COSMIC: NUTF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102898ENST00000219169P61970
ENSG00000102898ENST00000219169A0A024R6Y2
ENSG00000102898ENST00000567105H3BRV9
ENSG00000102898ENST00000568396P61970
ENSG00000102898ENST00000568396A0A024R6Y2
ENSG00000102898ENST00000569436P61970
ENSG00000102898ENST00000569436A0A024R6Y2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
268236042016Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding.17
182669112008A new role for nuclear transport factor 2 and Ran: nuclear import of CapG.12
155222852004Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.8
194044862009Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy.7
211957112011Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells.3
228800062012Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.3
290177492017Characterization of the nuclear import pathway for BLM protein.1

Citation

Dessen P

NUTF2 (nuclear transport factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53147/nutf2