Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NXF3 (nuclear RNA export factor 3)

Identity

Other alias-
HGNC (Hugo) NXF3
LocusID (NCBI) 56000
Atlas_Id 47228
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 103075821 and ends at 103093094 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NXF3 (Xq22.1) / GOLGA8A (15q14)RNF44 (5q35.2) / NXF3 (Xq22.1)RNF44 5q35.2 / NXF3 Xq22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(X;5)(q22;q35) RNF44/NXF3

External links

Nomenclature
HGNC (Hugo)NXF3   8073
Cards
Entrez_Gene (NCBI)NXF3  56000  nuclear RNA export factor 3
Aliases
GeneCards (Weizmann)NXF3
Ensembl hg19 (Hinxton)ENSG00000147206 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147206 [Gene_View]  ENSG00000147206 [Sequence]  chrX:103075821-103093094 [Contig_View]  NXF3 [Vega]
ICGC DataPortalENSG00000147206
TCGA cBioPortalNXF3
AceView (NCBI)NXF3
Genatlas (Paris)NXF3
WikiGenes56000
SOURCE (Princeton)NXF3
Genetics Home Reference (NIH)NXF3
Genomic and cartography
GoldenPath hg38 (UCSC)NXF3  -     chrX:103075821-103093094 -  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NXF3  -     Xq22.1   [Description]    (hg19-Feb_2009)
GoldenPathNXF3 - Xq22.1 [CytoView hg19]  NXF3 - Xq22.1 [CytoView hg38]
ImmunoBaseENSG00000147206
Mapping of homologs : NCBINXF3 [Mapview hg19]  NXF3 [Mapview hg38]
OMIM300316   
Gene and transcription
Genbank (Entrez)AF346619 AJ277527 AJ277660 AK057086 AK294826
RefSeq transcript (Entrez)NM_022052
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NXF3
Cluster EST : UnigeneHs.60386 [ NCBI ]
CGAP (NCI)Hs.60386
Alternative Splicing GalleryENSG00000147206
Gene ExpressionNXF3 [ NCBI-GEO ]   NXF3 [ EBI - ARRAY_EXPRESS ]   NXF3 [ SEEK ]   NXF3 [ MEM ]
Gene Expression Viewer (FireBrowse)NXF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56000
GTEX Portal (Tissue expression)NXF3
Human Protein AtlasENSG00000147206-NXF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4D5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4D5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4D5
Splice isoforms : SwissVarQ9H4D5
PhosPhoSitePlusQ9H4D5
Domaine pattern : Prosite (Expaxy)NTF2_DOMAIN (PS50177)   
Domains : Interpro (EBI)LRR_dom_sf    NTF2    NTF2-like_dom_sf    Nuclear_transport_factor_2_euk    Nucleotide-bd_a/b_plait_sf    NXF3    NXF_fam    RBD_domain_sf    Tap_RNA-bd   
Domain families : Pfam (Sanger)NTF2 (PF02136)    Tap-RNA_bind (PF09162)   
Domain families : Pfam (NCBI)pfam02136    pfam09162   
Domain structure : Prodom (Prabi Lyon)Tap_RNA_bd (PD043466)   
Conserved Domain (NCBI)NXF3
DMDM Disease mutations56000
Blocks (Seattle)NXF3
SuperfamilyQ9H4D5
Human Protein Atlas [tissue]ENSG00000147206-NXF3 [tissue]
Peptide AtlasQ9H4D5
HPRD02261
IPIIPI00004930   IPI00908372   IPI00909092   IPI00872823   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4D5
IntAct (EBI)Q9H4D5
FunCoupENSG00000147206
BioGRIDNXF3
STRING (EMBL)NXF3
ZODIACNXF3
Ontologies - Pathways
QuickGOQ9H4D5
Ontology : AmiGORNA binding  mRNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  mRNA export from nucleus  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  
Ontology : EGO-EBIRNA binding  mRNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  mRNA export from nucleus  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  
Pathways : KEGGRibosome biogenesis in eukaryotes    RNA transport    mRNA surveillance pathway    Influenza A    Herpes simplex infection   
NDEx NetworkNXF3
Atlas of Cancer Signalling NetworkNXF3
Wikipedia pathwaysNXF3
Orthology - Evolution
OrthoDB56000
GeneTree (enSembl)ENSG00000147206
Phylogenetic Trees/Animal Genes : TreeFamNXF3
HOGENOMQ9H4D5
Homologs : HomoloGeneNXF3
Homology/Alignments : Family Browser (UCSC)NXF3
Gene fusions - Rearrangements
Fusion : MitelmanRNF44/NXF3 [5q35.2/Xq22.1]  [t(X;5)(q22;q35)]  
Fusion PortalRNF44 5q35.2 NXF3 Xq22.1 BRCA
Fusion : QuiverNXF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNXF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NXF3
dbVarNXF3
ClinVarNXF3
1000_GenomesNXF3 
Exome Variant ServerNXF3
ExAC (Exome Aggregation Consortium)ENSG00000147206
GNOMAD BrowserENSG00000147206
Varsome BrowserNXF3
Genetic variants : HAPMAP56000
Genomic Variants (DGV)NXF3 [DGVbeta]
DECIPHERNXF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNXF3 
Mutations
ICGC Data PortalNXF3 
TCGA Data PortalNXF3 
Broad Tumor PortalNXF3
OASIS PortalNXF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNXF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNXF3
Mutations and Diseases : HGMDNXF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch NXF3
DgiDB (Drug Gene Interaction Database)NXF3
DoCM (Curated mutations)NXF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NXF3 (select a term)
intoGenNXF3
Cancer3DNXF3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300316   
Orphanet
DisGeNETNXF3
MedgenNXF3
Genetic Testing Registry NXF3
NextProtQ9H4D5 [Medical]
TSGene56000
GENETestsNXF3
Target ValidationNXF3
Huge Navigator NXF3 [HugePedia]
snp3D : Map Gene to Disease56000
BioCentury BCIQNXF3
ClinGenNXF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56000
Chemical/Pharm GKB GenePA31860
Clinical trialNXF3
Miscellaneous
canSAR (ICR)NXF3 (select the gene name)
DataMed IndexNXF3
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNXF3
EVEXNXF3
GoPubMedNXF3
iHOPNXF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:58:57 CET 2019
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