OARD1 (O-acyl-ADP-ribose deacylase 1)

2014-11-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
C6orf130,TARG1,dJ34B21.3

Other Information

Locus ID:

NCBI: 221443
MIM: 614393
HGNC: 21257
Ensembl: ENSG00000124596

Variants:

dbSNP: 221443
ClinVar: 221443
TCGA: ENSG00000124596
COSMIC: OARD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124596ENST00000373154C9J5P1
ENSG00000124596ENST00000424266Q9Y530
ENSG00000124596ENST00000424266A0A024RCY9
ENSG00000124596ENST00000463088Q9Y530
ENSG00000124596ENST00000463088A0A024RCY9
ENSG00000124596ENST00000464633C9JA90
ENSG00000124596ENST00000468811Q9Y530
ENSG00000124596ENST00000468811A0A024RCY9
ENSG00000124596ENST00000469104C9IZY1
ENSG00000124596ENST00000471367C9IZY1
ENSG00000124596ENST00000479950Q9Y530
ENSG00000124596ENST00000479950A0A024RCY9
ENSG00000124596ENST00000480585C9J5P1
ENSG00000124596ENST00000482515C9JA90
ENSG00000124596ENST00000482853H7C5Q1
ENSG00000124596ENST00000486443C9JXC3
ENSG00000124596ENST00000488238C9JNE2
ENSG00000124596ENST00000628419C9J5P1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
234812552013Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.109
260913422015Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.75
218495062011Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties.33

Citation

Dessen P

OARD1 (O-acyl-ADP-ribose deacylase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71080/oard1