Atlas of Genetics and Cytogenetics in Oncology and Haematology

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OLFM1 (olfactomedin 1)

Identity

Alias_symbol (synonym)NOE1
OlfA
AMY
NOELIN
Other aliasNOELIN1
HGNC (Hugo) OLFM1
LocusID (NCBI) 10439
Atlas_Id 57001
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 135075243 and ends at 135121184 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARIH1 (15q24.1) / OLFM1 (9q34.3)FAM129B (9q33.3) / OLFM1 (9q34.3)OLFM1 (9q34.3) / OLFM1 (9q34.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  FAM129B/OLFM1 (9q34)

External links

Nomenclature
HGNC (Hugo)OLFM1   17187
Cards
Entrez_Gene (NCBI)OLFM1  10439  olfactomedin 1
AliasesAMY; NOE1; NOELIN1; OlfA
GeneCards (Weizmann)OLFM1
Ensembl hg19 (Hinxton)ENSG00000130558 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130558 [Gene_View]  ENSG00000130558 [Sequence]  chr9:135075243-135121184 [Contig_View]  OLFM1 [Vega]
ICGC DataPortalENSG00000130558
TCGA cBioPortalOLFM1
AceView (NCBI)OLFM1
Genatlas (Paris)OLFM1
WikiGenes10439
SOURCE (Princeton)OLFM1
Genetics Home Reference (NIH)OLFM1
Genomic and cartography
GoldenPath hg38 (UCSC)OLFM1  -     chr9:135075243-135121184 +  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OLFM1  -     9q34.3   [Description]    (hg19-Feb_2009)
GoldenPathOLFM1 - 9q34.3 [CytoView hg19]  OLFM1 - 9q34.3 [CytoView hg38]
ImmunoBaseENSG00000130558
Mapping of homologs : NCBIOLFM1 [Mapview hg19]  OLFM1 [Mapview hg38]
OMIM605366   
Gene and transcription
Genbank (Entrez)AF035301 AI656802 AK090818 AK096304 AK289719
RefSeq transcript (Entrez)NM_001282611 NM_001282612 NM_006334 NM_014279 NM_058199
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OLFM1
Cluster EST : UnigeneHs.522484 [ NCBI ]
CGAP (NCI)Hs.522484
Alternative Splicing GalleryENSG00000130558
Gene ExpressionOLFM1 [ NCBI-GEO ]   OLFM1 [ EBI - ARRAY_EXPRESS ]   OLFM1 [ SEEK ]   OLFM1 [ MEM ]
Gene Expression Viewer (FireBrowse)OLFM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10439
GTEX Portal (Tissue expression)OLFM1
Human Protein AtlasENSG00000130558-OLFM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99784   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99784  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99784
Splice isoforms : SwissVarQ99784
PhosPhoSitePlusQ99784
Domaine pattern : Prosite (Expaxy)ER_TARGET (PS00014)    OLF (PS51132)   
Domains : Interpro (EBI)Noelin    Noelin_dom    Olfac-like_dom    Quino_amine_DH_bsu   
Domain families : Pfam (Sanger)Noelin-1 (PF12308)    OLF (PF02191)   
Domain families : Pfam (NCBI)pfam12308    pfam02191   
Domain families : Smart (EMBL)OLF (SM00284)  
Conserved Domain (NCBI)OLFM1
DMDM Disease mutations10439
Blocks (Seattle)OLFM1
PDB (RSDB)4XAT   
PDB Europe4XAT   
PDB (PDBSum)4XAT   
PDB (IMB)4XAT   
Structural Biology KnowledgeBase4XAT   
SCOP (Structural Classification of Proteins)4XAT   
CATH (Classification of proteins structures)4XAT   
SuperfamilyQ99784
Human Protein Atlas [tissue]ENSG00000130558-OLFM1 [tissue]
Peptide AtlasQ99784
IPIIPI00017841   IPI00419820   IPI00472517   IPI00419822   IPI00450167   IPI00550145   IPI00872826   IPI00480101   IPI01014733   IPI01015218   IPI01012513   IPI01009367   
Protein Interaction databases
DIP (DOE-UCLA)Q99784
IntAct (EBI)Q99784
FunCoupENSG00000130558
BioGRIDOLFM1
STRING (EMBL)OLFM1
ZODIACOLFM1
Ontologies - Pathways
QuickGOQ99784
Ontology : AmiGOatrioventricular valve formation  protein binding  extracellular space  cell  endoplasmic reticulum  nervous system development  positive regulation of gene expression  negative regulation of gene expression  positive regulation of epithelial to mesenchymal transition  neuronal signal transduction  cell junction  axon  regulation of axon extension  neuronal cell body  positive regulation of apoptotic process  perikaryon  axonal growth cone  synapse  cardiac epithelial to mesenchymal transition  
Ontology : EGO-EBIatrioventricular valve formation  protein binding  extracellular space  cell  endoplasmic reticulum  nervous system development  positive regulation of gene expression  negative regulation of gene expression  positive regulation of epithelial to mesenchymal transition  neuronal signal transduction  cell junction  axon  regulation of axon extension  neuronal cell body  positive regulation of apoptotic process  perikaryon  axonal growth cone  synapse  cardiac epithelial to mesenchymal transition  
NDEx NetworkOLFM1
Atlas of Cancer Signalling NetworkOLFM1
Wikipedia pathwaysOLFM1
Orthology - Evolution
OrthoDB10439
GeneTree (enSembl)ENSG00000130558
Phylogenetic Trees/Animal Genes : TreeFamOLFM1
HOGENOMQ99784
Homologs : HomoloGeneOLFM1
Homology/Alignments : Family Browser (UCSC)OLFM1
Gene fusions - Rearrangements
Fusion : QuiverOLFM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOLFM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OLFM1
dbVarOLFM1
ClinVarOLFM1
1000_GenomesOLFM1 
Exome Variant ServerOLFM1
ExAC (Exome Aggregation Consortium)ENSG00000130558
GNOMAD BrowserENSG00000130558
Varsome BrowserOLFM1
Genetic variants : HAPMAP10439
Genomic Variants (DGV)OLFM1 [DGVbeta]
DECIPHEROLFM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOLFM1 
Mutations
ICGC Data PortalOLFM1 
TCGA Data PortalOLFM1 
Broad Tumor PortalOLFM1
OASIS PortalOLFM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOLFM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOLFM1
Mutations and Diseases : HGMDOLFM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OLFM1
DgiDB (Drug Gene Interaction Database)OLFM1
DoCM (Curated mutations)OLFM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OLFM1 (select a term)
intoGenOLFM1
Cancer3DOLFM1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605366   
Orphanet
DisGeNETOLFM1
MedgenOLFM1
Genetic Testing Registry OLFM1
NextProtQ99784 [Medical]
TSGene10439
GENETestsOLFM1
Target ValidationOLFM1
Huge Navigator OLFM1 [HugePedia]
snp3D : Map Gene to Disease10439
BioCentury BCIQOLFM1
ClinGenOLFM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10439
Chemical/Pharm GKB GenePA31915
Clinical trialOLFM1
Miscellaneous
canSAR (ICR)OLFM1 (select the gene name)
DataMed IndexOLFM1
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOLFM1
EVEXOLFM1
GoPubMedOLFM1
iHOPOLFM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:59:06 CET 2019
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