Atlas of Genetics and Cytogenetics in Oncology and Haematology


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OLIG1 (oligodendrocyte transcription factor 1)

Identity

Alias (NCBI)BHLHB6
BHLHE21
HGNC (Hugo) OLIG1
HGNC Alias symbBHLHB6
bHLHe21
HGNC Alias nameoligodendrocyte-specific bHLH transcription factor 1
 oligodendrocyte lineage transcription factor 1
 basic domain, helix-loop-helix protein, class B, 6
LocusID (NCBI) 116448
Atlas_Id 49814
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 33070141 and ends at 33072413 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OLIG1   16983
Cards
Entrez_Gene (NCBI)OLIG1  116448  oligodendrocyte transcription factor 1
AliasesBHLHB6; BHLHE21
GeneCards (Weizmann)OLIG1
Ensembl hg19 (Hinxton)ENSG00000184221 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184221 [Gene_View]  ENSG00000184221 [Sequence]  chr21:33070141-33072413 [Contig_View]  OLIG1 [Vega]
ICGC DataPortalENSG00000184221
TCGA cBioPortalOLIG1
AceView (NCBI)OLIG1
Genatlas (Paris)OLIG1
WikiGenes116448
SOURCE (Princeton)OLIG1
Genetics Home Reference (NIH)OLIG1
Genomic and cartography
GoldenPath hg38 (UCSC)OLIG1  -     chr21:33070141-33072413 +  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OLIG1  -     21q22.11   [Description]    (hg19-Feb_2009)
GoldenPathOLIG1 - 21q22.11 [CytoView hg19]  OLIG1 - 21q22.11 [CytoView hg38]
ImmunoBaseENSG00000184221
genome Data Viewer NCBIOLIG1 [Mapview hg19]  
OMIM606385   
Gene and transcription
Genbank (Entrez)AB209791 AL355743 AL834450 AW298788 BC011252
RefSeq transcript (Entrez)NM_138983
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OLIG1
Alternative Splicing GalleryENSG00000184221
Gene ExpressionOLIG1 [ NCBI-GEO ]   OLIG1 [ EBI - ARRAY_EXPRESS ]   OLIG1 [ SEEK ]   OLIG1 [ MEM ]
Gene Expression Viewer (FireBrowse)OLIG1 [ Firebrowse - Broad ]
GenevisibleExpression of OLIG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116448
GTEX Portal (Tissue expression)OLIG1
Human Protein AtlasENSG00000184221-OLIG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TAK6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TAK6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TAK6
Splice isoforms : SwissVarQ8TAK6
PhosPhoSitePlusQ8TAK6
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    HLH_DNA-bd_sf    Olig1   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)OLIG1
DMDM Disease mutations116448
Blocks (Seattle)OLIG1
SuperfamilyQ8TAK6
Human Protein Atlas [tissue]ENSG00000184221-OLIG1 [tissue]
Peptide AtlasQ8TAK6
HPRD07333
IPIIPI00152068   IPI00894543   
Protein Interaction databases
DIP (DOE-UCLA)Q8TAK6
IntAct (EBI)Q8TAK6
FunCoupENSG00000184221
BioGRIDOLIG1
STRING (EMBL)OLIG1
ZODIACOLIG1
Ontologies - Pathways
QuickGOQ8TAK6
Ontology : AmiGOnuclear chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  regulation of transcription by RNA polymerase II  oligodendrocyte development  protein dimerization activity  neuron fate commitment  
Ontology : EGO-EBInuclear chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  regulation of transcription by RNA polymerase II  oligodendrocyte development  protein dimerization activity  neuron fate commitment  
NDEx NetworkOLIG1
Atlas of Cancer Signalling NetworkOLIG1
Wikipedia pathwaysOLIG1
Orthology - Evolution
OrthoDB116448
GeneTree (enSembl)ENSG00000184221
Phylogenetic Trees/Animal Genes : TreeFamOLIG1
HOGENOMQ8TAK6
Homologs : HomoloGeneOLIG1
Homology/Alignments : Family Browser (UCSC)OLIG1
Gene fusions - Rearrangements
Fusion : QuiverOLIG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOLIG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OLIG1
dbVarOLIG1
ClinVarOLIG1
1000_GenomesOLIG1 
Exome Variant ServerOLIG1
GNOMAD BrowserENSG00000184221
Varsome BrowserOLIG1
Genetic variants : HAPMAP116448
Genomic Variants (DGV)OLIG1 [DGVbeta]
DECIPHEROLIG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOLIG1 
Mutations
ICGC Data PortalOLIG1 
TCGA Data PortalOLIG1 
Broad Tumor PortalOLIG1
OASIS PortalOLIG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOLIG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOLIG1
Mutations and Diseases : HGMDOLIG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OLIG1
DgiDB (Drug Gene Interaction Database)OLIG1
DoCM (Curated mutations)OLIG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OLIG1 (select a term)
intoGenOLIG1
Cancer3DOLIG1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606385   
Orphanet
DisGeNETOLIG1
MedgenOLIG1
Genetic Testing Registry OLIG1
NextProtQ8TAK6 [Medical]
TSGene116448
GENETestsOLIG1
Target ValidationOLIG1
Huge Navigator OLIG1 [HugePedia]
snp3D : Map Gene to Disease116448
BioCentury BCIQOLIG1
ClinGenOLIG1
Clinical trials, drugs, therapy
Protein Interactions : CTD116448
Pharm GKB GenePA31918
Clinical trialOLIG1
Miscellaneous
canSAR (ICR)OLIG1 (select the gene name)
HarmonizomeOLIG1
DataMed IndexOLIG1
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOLIG1
EVEXOLIG1
GoPubMedOLIG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:28:09 CEST 2020

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