Identity
HGNC
LOCATION
15q21.3
LOCUSID
ALIAS
HNF-6,HNF6,HNF6A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3175
MIM: 604164
HGNC: 8138
Ensembl: ENSG00000169856
Variants:
dbSNP: 3175
ClinVar: 3175
TCGA: ENSG00000169856
COSMIC: ONECUT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169856 | ENST00000305901 | Q9UBC0 |
| ENSG00000169856 | ENST00000560699 | H0YMS2 |
| ENSG00000169856 | ENST00000570208 | U3KQR8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35482136 | 2022 | Contribution of ONECUT1 variants to different forms of non-autoimmune diabetes mellitus in Italian patients. | 2 |
| 35482136 | 2022 | Contribution of ONECUT1 variants to different forms of non-autoimmune diabetes mellitus in Italian patients. | 2 |
| 34663987 | 2021 | Mutations and variants of ONECUT1 in diabetes. | 14 |
| 34789845 | 2021 | Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation. | 11 |
| 34663987 | 2021 | Mutations and variants of ONECUT1 in diabetes. | 14 |
| 34789845 | 2021 | Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation. | 11 |
| 30256389 | 2019 | HNF6 promotes tumor growth in colorectal cancer and enhances liver metastasis in mouse model. | 3 |
| 31049588 | 2019 | ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility. | 27 |
| 30256389 | 2019 | HNF6 promotes tumor growth in colorectal cancer and enhances liver metastasis in mouse model. | 3 |
| 31049588 | 2019 | ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility. | 27 |
| 26825606 | 2016 | Hepatocyte nuclear factor 6 inhibits the growth and metastasis of cholangiocarcinoma cells by regulating miR-122. | 7 |
| 26825606 | 2016 | Hepatocyte nuclear factor 6 inhibits the growth and metastasis of cholangiocarcinoma cells by regulating miR-122. | 7 |
| 25653429 | 2015 | Inhibition of hepatitis B virus gene expression and replication by hepatocyte nuclear factor 6. | 21 |
| 25653429 | 2015 | Inhibition of hepatitis B virus gene expression and replication by hepatocyte nuclear factor 6. | 21 |
| 24638272 | 2014 | Loss of HNF6 expression correlates with human pancreatic cancer progression. | 12 |
Citation
Dessen P
ONECUT1 (one cut homeobox 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-06-01
Online version: http://atlasgeneticsoncology.org/gene/53307/onecut1
