OR1A1 (olfactory receptor family 1 subfamily A member 1)

2014-11-01  

Identity

HGNC
OR1A1
LOCATION
17p13.3
LOCUSID
8383
ALIAS
OR17-7

Other Information

Locus ID:

NCBI: 8383
MIM: 618046
HGNC: 8179
Ensembl: ENSG00000172146

Variants:

dbSNP: 8383
ClinVar: 8383
TCGA: ENSG00000172146
COSMIC: OR1A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172146ENST00000304094Q9P1Q5
ENSG00000172146ENST00000304094A0A126GWA2
ENSG00000172146ENST00000641322Q9P1Q5
ENSG00000172146ENST00000641322A0A126GWA2
ENSG00000172146ENST00000641732Q9P1Q5
ENSG00000172146ENST00000641732A0A126GWA2

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

References

Pubmed IDYearTitleCitations
176017482007Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2.48
258170412015Activation of OR1A1 suppresses PPAR-γ expression by inducing HES-1 in cultured hepatocytes.12
296321832018Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds.7

Citation

Dessen P

OR1A1 (olfactory receptor family 1 subfamily A member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71201/or1a1