OR2W3 (olfactory receptor family 2 subfamily W member 3)

2014-11-01  

Identity

HGNC
OR2W3
LOCATION
1q44
LOCUSID
343171
ALIAS
OR2W3P,OR2W8P,OST718

Other Information

Locus ID:

NCBI: 343171
MIM: 616729
HGNC: 15021
Ensembl: ENSG00000238243

Variants:

dbSNP: 343171
ClinVar: 343171
TCGA: ENSG00000238243
COSMIC: OR2W3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000238243ENST00000360358Q7Z3T1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
253743922015Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.2
257834832015Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa.0
258478452015Susceptibility to male infertility: replication study in Japanese men looking for an association with four GWAS-derived loci identified in European men.0
268910082016OR2W3 sequence variants are unlikely to cause inherited retinal diseases.0
279167482017OR2M3: A Highly Specific and Narrowly Tuned Human Odorant Receptor for the Sensitive Detection of Onion Key Food Odorant 3-Mercapto-2-methylpentan-1-ol.0
282620882017Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.0

Citation

Dessen P

OR2W3 (olfactory receptor family 2 subfamily W member 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71295/or2w3