Identity
HGNC
LOCATION
22q12.2
LOCUSID
ALIAS
HLM,ORP-4,ORP4,OSBPL1,OSBPL4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23762
MIM: 606729
HGNC: 8504
Ensembl: ENSG00000184792
Variants:
dbSNP: 23762
ClinVar: 23762
TCGA: ENSG00000184792
COSMIC: OSBP2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37903971 | 2023 | Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma. | 2 |
| 37903971 | 2023 | Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma. | 2 |
| 34797912 | 2022 | ORP4L is a prerequisite for the induction of T-cell leukemogenesis associated with human T-cell leukemia virus 1. | 4 |
| 34797912 | 2022 | ORP4L is a prerequisite for the induction of T-cell leukemogenesis associated with human T-cell leukemia virus 1. | 4 |
| 31648575 | 2019 | ORP4L couples IP(3) to ITPR1 in control of endoplasmic reticulum calcium release. | 9 |
| 31648575 | 2019 | ORP4L couples IP(3) to ITPR1 in control of endoplasmic reticulum calcium release. | 9 |
| 29930082 | 2018 | Golgi localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding. | 13 |
| 30237164 | 2018 | OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells. | 9 |
| 29930082 | 2018 | Golgi localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding. | 13 |
| 30237164 | 2018 | OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells. | 9 |
| 27581363 | 2016 | ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. | 33 |
| 27588468 | 2016 | Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca2+ homeostasis in cervical carcinoma cell lines. | 10 |
| 27729467 | 2016 | ORP4L Facilitates Macrophage Survival via G-Protein-Coupled Signaling: ORP4L-/- Mice Display a Reduction of Atherosclerosis. | 11 |
| 27581363 | 2016 | ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. | 33 |
| 27588468 | 2016 | Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca2+ homeostasis in cervical carcinoma cell lines. | 10 |
Citation
Dessen P
OSBP2 (oxysterol binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43794/osbp2
