OSTF1 (osteoclast stimulating factor 1)

2016-10-01  

Identity

HGNC
LOCATION
9q21.13
LOCUSID
ALIAS
OSF,SH3P2,bA235O14.1
FUSION GENES

Other Information

Locus ID:

NCBI: 26578
MIM: 610180
HGNC: 8510
Ensembl: ENSG00000134996

Variants:

dbSNP: 26578
ClinVar: 26578
TCGA: ENSG00000134996
COSMIC: OSTF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134996ENST00000346234Q92882

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.20
151350482004SH3P2 in complex with Cbl and Src.11
215013422011SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation.7
191375982009Crystal structure of human osteoclast stimulating factor.3
169464612006Structure of the SH3 domain of human osteoclast-stimulating factor at atomic resolution.1
293615512018Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling.1
165081122005Crystallization and preliminary X-ray crystallographic analysis of osteoclast-stimulating factor.0
204244732010L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.0

Citation

Dessen P

OSTF1 (osteoclast stimulating factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56037/ostf1