Identity
HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
HSPC263,OTB1,OTU1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55611
MIM: 608337
HGNC: 23077
Ensembl: ENSG00000167770
Variants:
dbSNP: 55611
ClinVar: 55611
TCGA: ENSG00000167770
COSMIC: OTUB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38266782 | 2024 | OTUB1 Targets CHK1 for Deubiquitination and Stabilization to Facilitate Lung Cancer Progression and Radioresistance. | 0 |
| 38315284 | 2024 | OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination. | 0 |
| 38462165 | 2024 | YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation. | 0 |
| 38644399 | 2024 | Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ. | 0 |
| 38814988 | 2024 | OTUB1 contributes to the stability and function of Influenza A virus NS2. | 0 |
| 38266782 | 2024 | OTUB1 Targets CHK1 for Deubiquitination and Stabilization to Facilitate Lung Cancer Progression and Radioresistance. | 0 |
| 38315284 | 2024 | OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination. | 0 |
| 38462165 | 2024 | YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation. | 0 |
| 38644399 | 2024 | Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ. | 0 |
| 38814988 | 2024 | OTUB1 contributes to the stability and function of Influenza A virus NS2. | 0 |
| 36272615 | 2023 | Mutant p53 driven-LINC00857, a protein scaffold between FOXM1 and deubiquitinase OTUB1, promotes the metastasis of pancreatic cancer. | 12 |
| 36822329 | 2023 | SET7 methylates the deubiquitinase OTUB1 at Lys (122) to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis. | 5 |
| 36976509 | 2023 | The Interaction of OTUB1 and TRAF3 Mediates NLRP3 Inflammasome Activity to Regulate TGF-β1-induced BEAS-2B Cell Injury. | 1 |
| 36994729 | 2023 | OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis. | 1 |
| 37532135 | 2023 | OTUB1's role in promoting OSCC development by stabilizing RACK1 involves cell proliferation, migration, invasion, and tumor-associated macrophage M1 polarization. | 1 |
Citation
Dessen P
OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Atlas Genet Cytogenet Oncol Haematol. 2004-04-01
Online version: http://atlasgeneticsoncology.org/gene/41619/otub1
