OVOL1 (ovo like transcriptional repressor 1)

2015-02-01  

Identity

HGNC
OVOL1
LOCATION
11q13.1
LOCUSID
5017
ALIAS
HOVO1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5017
MIM: 602313
HGNC: 8525
Ensembl: ENSG00000172818

Variants:

dbSNP: 5017
ClinVar: 5017
TCGA: ENSG00000172818
COSMIC: OVOL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172818ENST00000335987O14753
ENSG00000172818ENST00000532448G3V1B0

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
265042312015OVO-like 1 regulates progenitor cell fate in human trophoblast development.18
287038052017Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis.13
283394252017Potential role of the OVOL1-OVOL2 axis and c-Myc in the progression of cutaneous squamous cell carcinoma.9
232788452013Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients.8
268734472016Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma.8
227372372012Molecular phylogeny of OVOL genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions.6
261270032015Correlation of KIF3A and OVOL1, but not ACTL9, with atopic dermatitis in Chinese pediatric patients.4
255098832014Preferential expression of OVOL1 in inner root sheath of hair, sebaceous gland, eccrine duct and their neoplasms in human skin.1
306392122019OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates.1

Citation

Dessen P

OVOL1 (ovo like transcriptional repressor 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55015/ovol1