PACRG (parkin coregulated)

2007-02-01  

Identity

HGNC
LOCATION
6q26
LOCUSID
ALIAS
GLUP,HAK005771,PACRG2.1,PARK2CRG
FUSION GENES

Other Information

Locus ID:

NCBI: 135138
MIM: 608427
HGNC: 19152
Ensembl: ENSG00000112530

Variants:

dbSNP: 135138
ClinVar: 135138
TCGA: ENSG00000112530
COSMIC: PACRG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112530ENST00000337019Q96M98
ENSG00000112530ENST00000366888Q96M98
ENSG00000112530ENST00000366889Q96M98
ENSG00000112530ENST00000534958H0YGE0
ENSG00000112530ENST00000541974H0YFW3
ENSG00000112530ENST00000542936H0YFE8
ENSG00000112530ENST00000611387A0A087WXG4
ENSG00000112530ENST00000621363A0A087WT60

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
147371772004Susceptibility to leprosy is associated with PARK2 and PACRG.137
147371772004Susceptibility to leprosy is associated with PARK2 and PACRG.137
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200121772009Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis.44
125471872003Identification of a novel gene linked to parkin via a bi-directional promoter.30
162870632006Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia.23
197233942009Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians.20
230529432013Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy.18
145322702003A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17

Citation

Dessen P

PACRG (parkin coregulated)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45763/pacrg