Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5049
MIM: 602508
HGNC: 8575
Ensembl: ENSG00000168092
Variants:
dbSNP: 5049
ClinVar: 5049
TCGA: ENSG00000168092
COSMIC: PAFAH1B2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446108 | Colorectal Neoplasms | Disease | VariantAnnotation | not associated | PD | ||
| PA448497 | aspirin | Chemical | VariantAnnotation | not associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35462067 | 2022 | Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2. | 2 |
| 35462067 | 2022 | Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2. | 2 |
| 29758199 | 2018 | PAFAH1B2 is a HIF1a target gene and promotes metastasis in pancreatic cancer. | 15 |
| 29758199 | 2018 | PAFAH1B2 is a HIF1a target gene and promotes metastasis in pancreatic cancer. | 15 |
| 27910906 | 2016 | Analysis of the Serum Lipid Profile in Polypoidal Choroidal Vasculopathy. | 13 |
| 27910906 | 2016 | Analysis of the Serum Lipid Profile in Polypoidal Choroidal Vasculopathy. | 13 |
| 25945974 | 2015 | Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. | 26 |
| 25945974 | 2015 | Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. | 26 |
| 25034894 | 2014 | Associations of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms with circulating PAF-AH levels and risk of coronary heart disease or blood stasis syndrome in the Chinese Han population. | 7 |
| 25034894 | 2014 | Associations of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms with circulating PAF-AH levels and risk of coronary heart disease or blood stasis syndrome in the Chinese Han population. | 7 |
| 23508960 | 2013 | Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2). | 11 |
| 23508960 | 2013 | Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2). | 11 |
| 21866060 | 2012 | Plasma platelet-activating factor-acetyl hydrolase activity and the levels of free forms of biomarker of lipid peroxidation in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage. | 6 |
| 23238734 | 2012 | Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments. | 11 |
| 21866060 | 2012 | Plasma platelet-activating factor-acetyl hydrolase activity and the levels of free forms of biomarker of lipid peroxidation in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage. | 6 |
Citation
Dessen P
PAFAH1B2 (platelet activating factor acetylhydrolase 1b catalytic subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-01-01
Online version: http://atlasgeneticsoncology.org/gene/49979/pafah1b2
