PAGR1 (PAXIP1 associated glutamate rich protein 1)

2014-02-01  

Identity

HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
C16orf53,GAS,PA1
FUSION GENES

Other Information

Locus ID:

NCBI: 79447
MIM: 612033
HGNC: 28707
Ensembl: ENSG00000280789

Variants:

dbSNP: 79447
ClinVar: 79447
TCGA: ENSG00000280789
COSMIC: PAGR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000280789ENST00000320330Q9BTK6

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Activation of HOX genes during differentiationREACTOMER-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesisREACTOMER-HSA-5617472

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
175000652007PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.252
191244602009Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.37
231615822013PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation.14
190393272009GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function.7
242604162013PTIP associated protein 1, PA1, is an independent prognostic factor for lymphnode negative breast cancer.0
242604162013PTIP associated protein 1, PA1, is an independent prognostic factor for lymphnode negative breast cancer.0

Citation

Dessen P

PAGR1 (PAXIP1 associated glutamate rich protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-02-01

Online version: http://atlasgeneticsoncology.org/gene/53691/pagr1