Identity
HGNC
LOCATION
Xq23
LOCUSID
ALIAS
ARA,MRX30,MRX47,OPHN3,PAK-3,PAK3beta,bPAK,beta-PAK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5063
MIM: 300142
HGNC: 8592
Ensembl: ENSG00000077264
Variants:
dbSNP: 5063
ClinVar: 5063
TCGA: ENSG00000077264
COSMIC: PAK3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34381046 | 2021 | Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. | 23 |
| 34550532 | 2021 | PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth. | 3 |
| 34381046 | 2021 | Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. | 23 |
| 34550532 | 2021 | PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth. | 3 |
| 30890765 | 2020 | Prognostic significance of PAK family kinases in acute myeloid leukemia. | 11 |
| 31410926 | 2020 | Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease. | 23 |
| 31678216 | 2020 | Further delineation of the phenotype of PAK3-associated x-linked intellectual disability: Identification of a novel missense mutation and review of literature. | 3 |
| 31843706 | 2020 | PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration. | 10 |
| 31897927 | 2020 | Integration of hepatitis B virus DNA into p21-activated kinase 3 (PAK3) gene in HepG2.2.15 cells. | 6 |
| 31943058 | 2020 | The intellectual disability PAK3 R67C mutation impacts cognitive functions and adult hippocampal neurogenesis. | 7 |
| 32050918 | 2020 | Novel PAK3 gene missense variant associated with two Chinese siblings with intellectual disability: a case report. | 6 |
| 30890765 | 2020 | Prognostic significance of PAK family kinases in acute myeloid leukemia. | 11 |
| 31410926 | 2020 | Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease. | 23 |
| 31678216 | 2020 | Further delineation of the phenotype of PAK3-associated x-linked intellectual disability: Identification of a novel missense mutation and review of literature. | 3 |
| 31843706 | 2020 | PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration. | 10 |
Citation
Dessen P
PAK3 (p21 (RAC1) activated kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43392/pak3
