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PAPOLB (poly(A) polymerase beta)

Identity

Alias_namespoly(A) polymerase beta (testis specific)
Alias_symbol (synonym)PAPT
Other aliasTPAP
HGNC (Hugo) PAPOLB
LocusID (NCBI) 56903
Atlas_Id 71654
Location 7p22.1  [Link to chromosome band 7p22]
Location_base_pair Starts at 4857738 and ends at 4861994 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PAPOLB   15970
Cards
Entrez_Gene (NCBI)PAPOLB  56903  poly(A) polymerase beta
AliasesPAPT; TPAP
GeneCards (Weizmann)PAPOLB
Ensembl hg19 (Hinxton)ENSG00000218823 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000218823 [Gene_View]  ENSG00000218823 [Sequence]  chr7:4857738-4861994 [Contig_View]  PAPOLB [Vega]
ICGC DataPortalENSG00000218823
TCGA cBioPortalPAPOLB
AceView (NCBI)PAPOLB
Genatlas (Paris)PAPOLB
WikiGenes56903
SOURCE (Princeton)PAPOLB
Genetics Home Reference (NIH)PAPOLB
Genomic and cartography
GoldenPath hg38 (UCSC)PAPOLB  -     chr7:4857738-4861994 -  7p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAPOLB  -     7p22.1   [Description]    (hg19-Feb_2009)
GoldenPathPAPOLB - 7p22.1 [CytoView hg19]  PAPOLB - 7p22.1 [CytoView hg38]
ImmunoBaseENSG00000218823
genome Data Viewer NCBIPAPOLB [Mapview hg19]  
OMIM607436   
Gene and transcription
Genbank (Entrez)AF218840 AK312788 BC036653
RefSeq transcript (Entrez)NM_020144
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAPOLB
Alternative Splicing GalleryENSG00000218823
Gene ExpressionPAPOLB [ NCBI-GEO ]   PAPOLB [ EBI - ARRAY_EXPRESS ]   PAPOLB [ SEEK ]   PAPOLB [ MEM ]
Gene Expression Viewer (FireBrowse)PAPOLB [ Firebrowse - Broad ]
GenevisibleExpression of PAPOLB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56903
GTEX Portal (Tissue expression)PAPOLB
Human Protein AtlasENSG00000218823-PAPOLB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRJ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRJ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRJ5
Splice isoforms : SwissVarQ9NRJ5
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9NRJ5
Domains : Interpro (EBI)NuclTrfase_I-like_C    PolA_pol_cen_dom    PolA_pol_RNA-bd_dom    PolyA_polymerase    Polymerase_NTP_transf_dom   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_central (PF04928)    PAP_RNA-bind (PF04926)   
Domain families : Pfam (NCBI)pfam01909    pfam04928    pfam04926   
Conserved Domain (NCBI)PAPOLB
DMDM Disease mutations56903
Blocks (Seattle)PAPOLB
SuperfamilyQ9NRJ5
Human Protein Atlas [tissue]ENSG00000218823-PAPOLB [tissue]
Peptide AtlasQ9NRJ5
HPRD08467
IPIIPI00024525   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRJ5
IntAct (EBI)Q9NRJ5
FunCoupENSG00000218823
BioGRIDPAPOLB
STRING (EMBL)PAPOLB
ZODIACPAPOLB
Ontologies - Pathways
QuickGOQ9NRJ5
Ontology : AmiGORNA binding  polynucleotide adenylyltransferase activity  ATP binding  nucleus  cytoplasm  mRNA polyadenylation  metal ion binding  
Ontology : EGO-EBIRNA binding  polynucleotide adenylyltransferase activity  ATP binding  nucleus  cytoplasm  mRNA polyadenylation  metal ion binding  
NDEx NetworkPAPOLB
Atlas of Cancer Signalling NetworkPAPOLB
Wikipedia pathwaysPAPOLB
Orthology - Evolution
OrthoDB56903
GeneTree (enSembl)ENSG00000218823
Phylogenetic Trees/Animal Genes : TreeFamPAPOLB
HOGENOMQ9NRJ5
Homologs : HomoloGenePAPOLB
Homology/Alignments : Family Browser (UCSC)PAPOLB
Gene fusions - Rearrangements
Fusion : QuiverPAPOLB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAPOLB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAPOLB
dbVarPAPOLB
ClinVarPAPOLB
1000_GenomesPAPOLB 
Exome Variant ServerPAPOLB
GNOMAD BrowserENSG00000218823
Varsome BrowserPAPOLB
Genetic variants : HAPMAP56903
Genomic Variants (DGV)PAPOLB [DGVbeta]
DECIPHERPAPOLB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAPOLB 
Mutations
ICGC Data PortalPAPOLB 
TCGA Data PortalPAPOLB 
Broad Tumor PortalPAPOLB
OASIS PortalPAPOLB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAPOLB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPAPOLB
Mutations and Diseases : HGMDPAPOLB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAPOLB
DgiDB (Drug Gene Interaction Database)PAPOLB
DoCM (Curated mutations)PAPOLB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAPOLB (select a term)
intoGenPAPOLB
Cancer3DPAPOLB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607436   
Orphanet
DisGeNETPAPOLB
MedgenPAPOLB
Genetic Testing Registry PAPOLB
NextProtQ9NRJ5 [Medical]
TSGene56903
GENETestsPAPOLB
Target ValidationPAPOLB
Huge Navigator PAPOLB [HugePedia]
snp3D : Map Gene to Disease56903
BioCentury BCIQPAPOLB
ClinGenPAPOLB
Clinical trials, drugs, therapy
Protein Interactions : CTD56903
Pharm GKB GenePA32933
Clinical trialPAPOLB
Miscellaneous
canSAR (ICR)PAPOLB (select the gene name)
HarmonizomePAPOLB
DataMed IndexPAPOLB
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAPOLB
EVEXPAPOLB
GoPubMedPAPOLB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jul 10 20:30:34 CEST 2020
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