Identity
HGNC
LOCATION
10p11.22
LOCUSID
ALIAS
ASIP,Baz,PAR3,PAR3alpha,PARD-3,PARD3A,PPP1R118,SE2-5L16,SE2-5LT1,SE2-5T2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56288
MIM: 606745
HGNC: 16051
Ensembl: ENSG00000148498
Variants:
dbSNP: 56288
ClinVar: 56288
TCGA: ENSG00000148498
COSMIC: PARD3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38317186 | 2024 | PARD3 drives tumorigenesis through activating Sonic Hedgehog signalling in tumour-initiating cells in liver cancer. | 3 |
| 38711082 | 2024 | DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway. | 0 |
| 38317186 | 2024 | PARD3 drives tumorigenesis through activating Sonic Hedgehog signalling in tumour-initiating cells in liver cancer. | 3 |
| 38711082 | 2024 | DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway. | 0 |
| 37232035 | 2023 | Integrative analysis of cancer dependency data and comprehensive phosphoproteomics data revealed the EPHA2-PARD3 axis as a cancer vulnerability in KRAS-mutant colorectal cancer. | 1 |
| 37232035 | 2023 | Integrative analysis of cancer dependency data and comprehensive phosphoproteomics data revealed the EPHA2-PARD3 axis as a cancer vulnerability in KRAS-mutant colorectal cancer. | 1 |
| 33565714 | 2022 | Par-3 family proteins in cell polarity & adhesion. | 11 |
| 35079981 | 2022 | Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest. | 1 |
| 33565714 | 2022 | Par-3 family proteins in cell polarity & adhesion. | 11 |
| 35079981 | 2022 | Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest. | 1 |
| 33675651 | 2021 | Par3/integrin β1 regulates embryo adhesion via changing endometrial luminal epithelium polarity†. | 0 |
| 33931921 | 2021 | Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis. | 4 |
| 34023783 | 2021 | Loss of polarity protein Par3 is mediated by transcription factor Sp1 in breast cancer. | 2 |
| 34040099 | 2021 | High expression of PARD3 predicts poor prognosis in hepatocellular carcinoma. | 6 |
| 34216486 | 2021 | Par3 and ZO-1 Membrane Clustering is an Indicator of Poor Prognosis in Lung Squamous Cell Carcinoma. | 1 |
Citation
Dessen P
PARD3 (par-3 family cell polarity regulator)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/49754/pard3
