PARP12 (poly(ADP-ribose) polymerase family member 12)

2021-06-01  

Identity

HGNC
PARP12
LOCATION
7q34
LOCUSID
64761
ALIAS
ARTD12,MST109,MSTP109,ZC3H1,ZC3HDC1

Other Information

Locus ID:

NCBI: 64761
MIM: 612481
HGNC: 21919
Ensembl: ENSG00000059378

Variants:

dbSNP: 64761
ClinVar: 64761
TCGA: ENSG00000059378
COSMIC: PARP12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000059378ENST00000263549Q9H0J9
ENSG00000059378ENST00000263549A4D1T0
ENSG00000059378ENST00000473341G5E9U9
ENSG00000059378ENST00000484111H7C4Z9
ENSG00000059378ENST00000489809H7C4L8
ENSG00000059378ENST00000491598H7C4T3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
197296012009Candidate gene polymorphisms for ischemic stroke.14
128517072003Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31.9
301544092018PARP12 (ARTD12) suppresses hepatocellular carcinoma metastasis through interacting with FHL2 and regulating its stability.3

Citation

Dessen P

PARP12 (poly(ADP-ribose) polymerase family member 12)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58351/parp12