PARP9 (poly(ADP-ribose) polymerase family member 9)

2003-06-01  

Identity

HGNC
PARP9
LOCATION
3q21.1
LOCUSID
83666
ALIAS
ARTD9,BAL,BAL1,MGC:7868
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83666
MIM: 612065
HGNC: 24118
Ensembl: ENSG00000138496

Variants:

dbSNP: 83666
ClinVar: 83666
TCGA: ENSG00000138496
COSMIC: PARP9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138496ENST00000360356Q8IXQ6
ENSG00000138496ENST00000462315Q8IXQ6
ENSG00000138496ENST00000466126C9K0E5
ENSG00000138496ENST00000471785Q8IXQ6
ENSG00000138496ENST00000477522Q8IXQ6
ENSG00000138496ENST00000492382G5E9U8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Nicotinate metabolismREACTOMER-HSA-196807
Nicotinamide salvagingREACTOMER-HSA-197264

References

Pubmed IDYearTitleCitations
383447582024P. gingivalis-Induced TLR2 Interactome Analysis Reveals Association with PARP9.0
383447582024P. gingivalis-Induced TLR2 Interactome Analysis Reveals Association with PARP9.0
372001072023Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production.7
372001072023Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production.7
339761872021Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly.17
339762102021Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.47
343585602021The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling.57
339761872021Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly.17
339762102021Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.47
343585602021The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling.57
320204212020Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway.54
326785192020Molecular and clinical characterization of PARP9 in gliomas: A potential immunotherapeutic target.9
330605722020Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.36
320204212020Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway.54
326785192020Molecular and clinical characterization of PARP9 in gliomas: A potential immunotherapeutic target.9

Citation

Dessen P

PARP9 (poly(ADP-ribose) polymerase family member 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/753/parp9