PCBP4 (poly(rC) binding protein 4)

2003-06-01  

Identity

HGNC
LOCATION
3p21.2
LOCUSID
ALIAS
CBP,LIP4,MCG10
FUSION GENES

Other Information

Locus ID:

NCBI: 57060
MIM: 608503
HGNC: 8652
Ensembl: ENSG00000090097

Variants:

dbSNP: 57060
ClinVar: 57060
TCGA: ENSG00000090097
COSMIC: PCBP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090097ENST00000322099P57723
ENSG00000090097ENST00000322099A0A024R320
ENSG00000090097ENST00000355852P57723
ENSG00000090097ENST00000355852A0A024R320
ENSG00000090097ENST00000428823P57723
ENSG00000090097ENST00000461544C9K0A2
ENSG00000090097ENST00000461554P57723
ENSG00000090097ENST00000461554A0A024R320
ENSG00000090097ENST00000466412C9JTY5
ENSG00000090097ENST00000468324C9JZY3
ENSG00000090097ENST00000471308F8WC71
ENSG00000090097ENST00000471622C9J0A4
ENSG00000090097ENST00000483411C9IZV9
ENSG00000090097ENST00000484633P57723
ENSG00000090097ENST00000489595C9JSA6
ENSG00000090097ENST00000490063C9J7A9
ENSG00000090097ENST00000497653C9J5V4

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
Cell CycleREACTOMER-HSA-1640170
Cell Cycle CheckpointsREACTOMER-HSA-69620
G1/S DNA Damage CheckpointsREACTOMER-HSA-69615
p53-Dependent G1/S DNA damage checkpointREACTOMER-HSA-69580
p53-Dependent G1 DNA Damage ResponseREACTOMER-HSA-69563
Transcriptional activation of p53 responsive genesREACTOMER-HSA-69560
Transcriptional activation of cell cycle inhibitor p21REACTOMER-HSA-69895
TP53 Regulates Transcription of Cell Cycle GenesREACTOMER-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle ArrestREACTOMER-HSA-6804116

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
179732582008Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
261969572015Suppression of Poly(rC)-Binding Protein 4 (PCBP4) reduced cisplatin resistance in human maxillary cancer cells.2

Citation

Dessen P

PCBP4 (poly(rC) binding protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41662/pcbp4