Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
MEL-18,RNF110,TPFS,ZNF144
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7703
MIM: 600346
HGNC: 12929
Ensembl: ENSG00000277258
Variants:
dbSNP: 7703
ClinVar: 7703
TCGA: ENSG00000277258
COSMIC: PCGF2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35427425 | 2022 | SLCO4A1-AS1 triggers the malignant behaviours of melanoma cells via sponging miR-1306-5p to enhance PCGF2. | 2 |
| 35427425 | 2022 | SLCO4A1-AS1 triggers the malignant behaviours of melanoma cells via sponging miR-1306-5p to enhance PCGF2. | 2 |
| 33664452 | 2021 | AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation. | 3 |
| 33664452 | 2021 | AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation. | 3 |
| 27030546 | 2016 | PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. | 6 |
| 27542229 | 2016 | Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer. | 7 |
| 27030546 | 2016 | PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. | 6 |
| 27542229 | 2016 | Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer. | 7 |
| 25822021 | 2015 | MEL-18 loss mediates estrogen receptor-α downregulation and hormone independence. | 20 |
| 25822021 | 2015 | MEL-18 loss mediates estrogen receptor-α downregulation and hormone independence. | 20 |
| 23474752 | 2014 | Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. | 59 |
| 24964959 | 2014 | Expression and clinicopathological significance of Mel-18 mRNA in colorectal cancer. | 3 |
| 23474752 | 2014 | Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. | 59 |
| 24964959 | 2014 | Expression and clinicopathological significance of Mel-18 mRNA in colorectal cancer. | 3 |
| 22954590 | 2012 | Loss of Mel-18 enhances breast cancer stem cell activity and tumorigenicity through activating Notch signaling mediated by the Wnt/TCF pathway. | 24 |
Citation
Dessen P
PCGF2 (polycomb group ring finger 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42125/pcgf2
