Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
KEN,MOPD2,PCN,PCNT2,PCNTB,PCTN2,SCKL4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5116
MIM: 605925
HGNC: 16068
Ensembl: ENSG00000160299
Variants:
dbSNP: 5116
ClinVar: 5116
TCGA: ENSG00000160299
COSMIC: PCNT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160299 | ENST00000359568 | O95613 |
| ENSG00000160299 | ENST00000418394 | H7C2A3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37211383 | 2023 | PCNT is a prognostic biomarker correlated with tumor immune microenvironment in hepatocellular carcinoma and promotes tumor progression by inhibiting cell cycle arrest. | 0 |
| 37937642 | 2023 | Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation. | 0 |
| 37211383 | 2023 | PCNT is a prognostic biomarker correlated with tumor immune microenvironment in hepatocellular carcinoma and promotes tumor progression by inhibiting cell cycle arrest. | 0 |
| 37937642 | 2023 | Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation. | 0 |
| 33460028 | 2021 | Identification of three novel mutations in PCNT in vietnamese patients with microcephalic osteodysplastic primordial dwarfism type II. | 2 |
| 34233584 | 2021 | Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase. | 2 |
| 34418690 | 2021 | Coding variants in the PCNT and CEP295 genes contribute to breast cancer risk in Chinese women. | 2 |
| 33460028 | 2021 | Identification of three novel mutations in PCNT in vietnamese patients with microcephalic osteodysplastic primordial dwarfism type II. | 2 |
| 34233584 | 2021 | Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase. | 2 |
| 34418690 | 2021 | Coding variants in the PCNT and CEP295 genes contribute to breast cancer risk in Chinese women. | 2 |
| 32255253 | 2020 | Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. | 7 |
| 32267100 | 2020 | Microcephalic osteodysplastic primordial dwarfism type II: Additional nine patients with implications on phenotype and genotype correlation. | 5 |
| 32557621 | 2020 | Novel PCNT variants in MOPDII with attenuated growth restriction and pachygyria. | 3 |
| 32744776 | 2020 | Microcephalic osteodysplastic primordial dwarfism type II and pachygyria: Morphometric analysis in a 2-year-old girl. | 2 |
| 33170211 | 2020 | Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix. | 20 |
Citation
Dessen P
PCNT (pericentrin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46563/pcnt
