PDE7B (phosphodiesterase 7B)

2009-02-01  

Identity

HGNC
LOCATION
6q23.3
LOCUSID
ALIAS
bA472E5.1

Other Information

Locus ID:

NCBI: 27115
MIM: 604645
HGNC: 8792
Ensembl: ENSG00000171408

Variants:

dbSNP: 27115
ClinVar: 27115
TCGA: ENSG00000171408
COSMIC: PDE7B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171408ENST00000308191Q9NP56
ENSG00000171408ENST00000446774H0Y689
ENSG00000171408ENST00000615259A1E5M1

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Purine metabolismKEGGhsa00230
Morphine addictionKEGGhsa05032
Morphine addictionKEGGko05032
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
387783172024Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.0
387783172024Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.0
372917552023Role and mechanism of Circ-PDE7B in the formation of keloid.2
372917552023Role and mechanism of Circ-PDE7B in the formation of keloid.2
302093632019Phosphodiesterase 7B/microRNA-200c relationship regulates triple-negative breast cancer cell growth.18
317407422019The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia.5
302093632019Phosphodiesterase 7B/microRNA-200c relationship regulates triple-negative breast cancer cell growth.18
317407422019The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia.5
303233542018BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts.16
303233542018BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts.16
270929522016PDE7B, NMBR and EPM2A Variants and Schizophrenia: A Case-Control and Pharmacogenetics Study.4
270929522016PDE7B, NMBR and EPM2A Variants and Schizophrenia: A Case-Control and Pharmacogenetics Study.4
234531222013High expression of cyclic nucleotide phosphodiesterase 7B mRNA predicts poor prognosis in mantle cell lymphoma.5
234531222013High expression of cyclic nucleotide phosphodiesterase 7B mRNA predicts poor prognosis in mantle cell lymphoma.5
207989842011A cohort of balanced reciprocal translocations associated with dyslexia: identification of two putative candidate genes at DYX1.7

Citation

Dessen P

PDE7B (phosphodiesterase 7B)

Atlas Genet Cytogenet Oncol Haematol. 2009-02-01

Online version: http://atlasgeneticsoncology.org/gene/50676/pde7b